Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis
Aim: In the present study, the relationship between neonatal morbidity and cord vitamin D levels is investigated. Materials and Methods: Premature infants who were born before 32 weeks of gestation and admitted to our neonatal intensive care unit between January 2014 and January 2015 were included...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2018-03-01
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| Series: | Journal of Pediatric Research |
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| Online Access: | http://jpedres.org/archives/archive-detail/article-preview/vitamin-d-deficiency-in-premature-nfants-and-ts-ef/16907 |
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| author | Demet Terek Gizem Özcan Fırat Ergin Özge Altun Köroğlu Mehmet Yalaz Mete Akisu Nilgün Kültürsay |
| author_facet | Demet Terek Gizem Özcan Fırat Ergin Özge Altun Köroğlu Mehmet Yalaz Mete Akisu Nilgün Kültürsay |
| author_sort | Demet Terek |
| collection | DOAJ |
| description | Aim: In the present study, the relationship between neonatal morbidity and cord vitamin D levels is investigated.
Materials and Methods: Premature infants who were born before 32 weeks of gestation and admitted to our neonatal intensive care unit between January 2014 and January 2015 were included in the study. Vitamin D levels in the cord blood of infants were measured. Serum calcium, phosphorus and alkaline phosphatase levels were recorded in the first 24 hours. All neonates were followed up for neonatal morbidities until discharge.
Results: The mean gestational age of the study subjects was 29.2±2.6 (23-32). The mean vitamin D level was 27.4±19.3 ng/mL (4-76). Fourteen (46.7%) infants had normal vitamin D levels; 2 infants (6.7%) had vitamin D insufficiency (20-30 ng/mL), 14 infants (46.7%) had vitamin D deficiency (<20 ng/mL), and 7 infants had severe vitamin D deficiency (23.3%). In 60% of infants with intrauterine growth restriction had vitamin D deficiency of p<0.05. Serum phosphorus levels on the first day of life were significantly lower in infants with vitamin D deficiency (p<0.001).
Conclusion: In more than half of the study population vitamin D deficiency was determined. Infants with intrauterine growth restriction had vitamin D deficiency in more than half of the cases. Low levels of phosphorus may be a marker of vitamin D deficiency in the first days of life. |
| first_indexed | 2024-04-10T12:03:38Z |
| format | Article |
| id | doaj.art-713a12ea1c2e45ef929f98af21ab999a |
| institution | Directory Open Access Journal |
| issn | 2147-9445 |
| language | English |
| last_indexed | 2024-04-10T12:03:38Z |
| publishDate | 2018-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Pediatric Research |
| spelling | doaj.art-713a12ea1c2e45ef929f98af21ab999a2023-02-15T16:16:23ZengGalenos YayineviJournal of Pediatric Research2147-94452018-03-0151374010.4274/jpr.82788Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal PrognosisDemet Terek0Gizem Özcan1Fırat Ergin2Özge Altun Köroğlu3Mehmet Yalaz4Mete Akisu5Nilgün Kültürsay6Ege University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyEge University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyEge University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyEge University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyEge University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyEge University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyEge University Faculty fo Medicine, Department of Pediatrics, Division of Neonatology, İzmir, TurkeyAim: In the present study, the relationship between neonatal morbidity and cord vitamin D levels is investigated. Materials and Methods: Premature infants who were born before 32 weeks of gestation and admitted to our neonatal intensive care unit between January 2014 and January 2015 were included in the study. Vitamin D levels in the cord blood of infants were measured. Serum calcium, phosphorus and alkaline phosphatase levels were recorded in the first 24 hours. All neonates were followed up for neonatal morbidities until discharge. Results: The mean gestational age of the study subjects was 29.2±2.6 (23-32). The mean vitamin D level was 27.4±19.3 ng/mL (4-76). Fourteen (46.7%) infants had normal vitamin D levels; 2 infants (6.7%) had vitamin D insufficiency (20-30 ng/mL), 14 infants (46.7%) had vitamin D deficiency (<20 ng/mL), and 7 infants had severe vitamin D deficiency (23.3%). In 60% of infants with intrauterine growth restriction had vitamin D deficiency of p<0.05. Serum phosphorus levels on the first day of life were significantly lower in infants with vitamin D deficiency (p<0.001). Conclusion: In more than half of the study population vitamin D deficiency was determined. Infants with intrauterine growth restriction had vitamin D deficiency in more than half of the cases. Low levels of phosphorus may be a marker of vitamin D deficiency in the first days of life.http://jpedres.org/archives/archive-detail/article-preview/vitamin-d-deficiency-in-premature-nfants-and-ts-ef/16907Preterm birthvitamin Dintrauterine growth restriction |
| spellingShingle | Demet Terek Gizem Özcan Fırat Ergin Özge Altun Köroğlu Mehmet Yalaz Mete Akisu Nilgün Kültürsay Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis Journal of Pediatric Research Preterm birth vitamin D intrauterine growth restriction |
| title | Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis |
| title_full | Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis |
| title_fullStr | Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis |
| title_full_unstemmed | Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis |
| title_short | Vitamin D Deficiency in Premature Infants and Its Effects on Neonatal Prognosis |
| title_sort | vitamin d deficiency in premature infants and its effects on neonatal prognosis |
| topic | Preterm birth vitamin D intrauterine growth restriction |
| url | http://jpedres.org/archives/archive-detail/article-preview/vitamin-d-deficiency-in-premature-nfants-and-ts-ef/16907 |
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