Pertussis: Resurgence of a forgotten entity

Pertussis is a serious and life-threatening infection of infancy. Recurrent apnea with a paroxysm of cough is the early clue for its diagnosis. The rate of pertussis increased worldwide with the occurrence of regular outbreaks globally, including India. The resurgence of pertussis is multifactorial,...

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Main Authors: Mukesh Kumar Jain, Sibabratta Patnaik, Bandya Sahoo, Reshmi Mishra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Pediatric Critical Care
Subjects:
Online Access:http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2020;volume=7;issue=5;spage=276;epage=278;aulast=Jain
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author Mukesh Kumar Jain
Sibabratta Patnaik
Bandya Sahoo
Reshmi Mishra
author_facet Mukesh Kumar Jain
Sibabratta Patnaik
Bandya Sahoo
Reshmi Mishra
author_sort Mukesh Kumar Jain
collection DOAJ
description Pertussis is a serious and life-threatening infection of infancy. Recurrent apnea with a paroxysm of cough is the early clue for its diagnosis. The rate of pertussis increased worldwide with the occurrence of regular outbreaks globally, including India. The resurgence of pertussis is multifactorial, and it includes antigenic shifts in bacteria, decreasing vaccine immunity, reduced duration of protection by acellular pertussis vaccine, and improved method of surveillance and diagnosis. Family members, especially mothers and siblings, are an important source of pertussis transmission to vulnerable infants. Maternal vaccination for pertussis during pregnancy should be done as many cases of infantile pertussis was found before primary immunization. A 45 days infants admitted to the pediatric intensive care unit with recurrent apnea and bradycardia, require prolonged mechanical ventilation with intense cardiorespiratory monitoring. Real-time polymerase chain reaction of the nasopharyngeal swab for pertussis was positive. Successfully discharged after a long course of hospitalization.
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spelling doaj.art-713bdbcd2abb41ffa9ef04defb4fc53c2022-12-22T01:22:31ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992020-01-017527627810.4103/JPCC.JPCC_79_20Pertussis: Resurgence of a forgotten entityMukesh Kumar JainSibabratta PatnaikBandya SahooReshmi MishraPertussis is a serious and life-threatening infection of infancy. Recurrent apnea with a paroxysm of cough is the early clue for its diagnosis. The rate of pertussis increased worldwide with the occurrence of regular outbreaks globally, including India. The resurgence of pertussis is multifactorial, and it includes antigenic shifts in bacteria, decreasing vaccine immunity, reduced duration of protection by acellular pertussis vaccine, and improved method of surveillance and diagnosis. Family members, especially mothers and siblings, are an important source of pertussis transmission to vulnerable infants. Maternal vaccination for pertussis during pregnancy should be done as many cases of infantile pertussis was found before primary immunization. A 45 days infants admitted to the pediatric intensive care unit with recurrent apnea and bradycardia, require prolonged mechanical ventilation with intense cardiorespiratory monitoring. Real-time polymerase chain reaction of the nasopharyngeal swab for pertussis was positive. Successfully discharged after a long course of hospitalization.http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2020;volume=7;issue=5;spage=276;epage=278;aulast=Jainapneainfancypertussispolymerase chain reaction
spellingShingle Mukesh Kumar Jain
Sibabratta Patnaik
Bandya Sahoo
Reshmi Mishra
Pertussis: Resurgence of a forgotten entity
Journal of Pediatric Critical Care
apnea
infancy
pertussis
polymerase chain reaction
title Pertussis: Resurgence of a forgotten entity
title_full Pertussis: Resurgence of a forgotten entity
title_fullStr Pertussis: Resurgence of a forgotten entity
title_full_unstemmed Pertussis: Resurgence of a forgotten entity
title_short Pertussis: Resurgence of a forgotten entity
title_sort pertussis resurgence of a forgotten entity
topic apnea
infancy
pertussis
polymerase chain reaction
url http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2020;volume=7;issue=5;spage=276;epage=278;aulast=Jain
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AT sibabrattapatnaik pertussisresurgenceofaforgottenentity
AT bandyasahoo pertussisresurgenceofaforgottenentity
AT reshmimishra pertussisresurgenceofaforgottenentity