Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study
Abstract Background The effort to reduce the burden of malaria should target transmission in the community by accurate identification of asymptomatic infections. In malaria-endemic areas, asymptomatic malaria infection is still associated with complications. Malaria during pregnancy is characterized...
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| Format: | Article |
| Language: | English |
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BMC
2020-02-01
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| Series: | Malaria Journal |
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| Online Access: | https://doi.org/10.1186/s12936-020-3152-9 |
| _version_ | 1818408644888231936 |
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| author | Daniel Getacher Feleke Aderaw Adamu Angesom Gebreweld Melkam Tesfaye Wondmagegn Demisiss Genet Molla |
| author_facet | Daniel Getacher Feleke Aderaw Adamu Angesom Gebreweld Melkam Tesfaye Wondmagegn Demisiss Genet Molla |
| author_sort | Daniel Getacher Feleke |
| collection | DOAJ |
| description | Abstract Background The effort to reduce the burden of malaria should target transmission in the community by accurate identification of asymptomatic infections. In malaria-endemic areas, asymptomatic malaria infection is still associated with complications. Malaria during pregnancy is characterized by anaemia and placental malaria, leading to low birth weight and perinatal morbidity and mortality. This study aimed to provide reliable data on the burden of asymptomatic malaria among pregnant women in malaria endemic areas of North-Shoa, Ethiopia. Methods Cross-sectional study was carried out to assess the prevalence and predictors of asymptomatic malaria in pregnant women from November 2018 to January 2019. Multistage sampling technique was employed to include 263 study participants. Data were analysed using SPSS version 20.0 statistical software. In all comparisons, p-values ≤ 0.05 was considered as statistically significant. Results The prevalence of asymptomatic malaria infection was 5.7% (15/263) and 3.4% (9/263) by using microscopy and RDTs, respectively. Plasmodium falciparum was a dominant species 9 (3.4%) and Plasmodium vivax accounted for 6 (2.3%) of Plasmodium infections as detected by microscopy. Multivariate analysis showed that ITN usage and haemoglobin level had a statistically significant association with Plasmodium infection after adjusting other possible factors. Compared to those who were using ITN always, the odds of Plasmodium infection was 18.16 times higher (95% CI 1.84–179.07) in pregnant women who were not using ITN, and 5.19 times higher (95% CI 0.55–49.21) in pregnant women who were using ITN sometimes. Asymptomatic malaria infected pregnant women were 3.78 times (95% CI 0.98–14.58) more likely to be anaemic compared to non-infected pregnant women. Conclusion The present study showed asymptomatic malaria is prevalent in pregnant women and it has statistically significance association with the haemoglobin level of pregnant women. This indicates pregnant women have to be screened for asymptomatic malaria to avoid health consequences of malaria infection during pregnancy for the mother and fetus. |
| first_indexed | 2024-12-14T09:47:01Z |
| format | Article |
| id | doaj.art-713e417ea1a140f88f421e8e8da1b248 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-14T09:47:01Z |
| publishDate | 2020-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-713e417ea1a140f88f421e8e8da1b2482022-12-21T23:07:37ZengBMCMalaria Journal1475-28752020-02-011911610.1186/s12936-020-3152-9Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional studyDaniel Getacher Feleke0Aderaw Adamu1Angesom Gebreweld2Melkam Tesfaye3Wondmagegn Demisiss4Genet Molla5Departmentof Medical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityDepartmentof Medical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityDepartmentof Medical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityDepartmentof Medical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityDepartmentof Medical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityDepartmentof Medical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityAbstract Background The effort to reduce the burden of malaria should target transmission in the community by accurate identification of asymptomatic infections. In malaria-endemic areas, asymptomatic malaria infection is still associated with complications. Malaria during pregnancy is characterized by anaemia and placental malaria, leading to low birth weight and perinatal morbidity and mortality. This study aimed to provide reliable data on the burden of asymptomatic malaria among pregnant women in malaria endemic areas of North-Shoa, Ethiopia. Methods Cross-sectional study was carried out to assess the prevalence and predictors of asymptomatic malaria in pregnant women from November 2018 to January 2019. Multistage sampling technique was employed to include 263 study participants. Data were analysed using SPSS version 20.0 statistical software. In all comparisons, p-values ≤ 0.05 was considered as statistically significant. Results The prevalence of asymptomatic malaria infection was 5.7% (15/263) and 3.4% (9/263) by using microscopy and RDTs, respectively. Plasmodium falciparum was a dominant species 9 (3.4%) and Plasmodium vivax accounted for 6 (2.3%) of Plasmodium infections as detected by microscopy. Multivariate analysis showed that ITN usage and haemoglobin level had a statistically significant association with Plasmodium infection after adjusting other possible factors. Compared to those who were using ITN always, the odds of Plasmodium infection was 18.16 times higher (95% CI 1.84–179.07) in pregnant women who were not using ITN, and 5.19 times higher (95% CI 0.55–49.21) in pregnant women who were using ITN sometimes. Asymptomatic malaria infected pregnant women were 3.78 times (95% CI 0.98–14.58) more likely to be anaemic compared to non-infected pregnant women. Conclusion The present study showed asymptomatic malaria is prevalent in pregnant women and it has statistically significance association with the haemoglobin level of pregnant women. This indicates pregnant women have to be screened for asymptomatic malaria to avoid health consequences of malaria infection during pregnancy for the mother and fetus.https://doi.org/10.1186/s12936-020-3152-9Asymptomatic malariaAnaemiaPregnant womenPrevalencePlasmodium speciesEthiopia |
| spellingShingle | Daniel Getacher Feleke Aderaw Adamu Angesom Gebreweld Melkam Tesfaye Wondmagegn Demisiss Genet Molla Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study Malaria Journal Asymptomatic malaria Anaemia Pregnant women Prevalence Plasmodium species Ethiopia |
| title | Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study |
| title_full | Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study |
| title_fullStr | Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study |
| title_full_unstemmed | Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study |
| title_short | Asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of North-Shoa, Ethiopia: a cross-sectional study |
| title_sort | asymptomatic malaria infection among pregnant women attending antenatal care in malaria endemic areas of north shoa ethiopia a cross sectional study |
| topic | Asymptomatic malaria Anaemia Pregnant women Prevalence Plasmodium species Ethiopia |
| url | https://doi.org/10.1186/s12936-020-3152-9 |
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