The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients
Background: Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles. It is one of the most important skin disorders during adolescence. Zinc is one of essential trace elements in the body that has major roles in maintaining health. The main objectives of this study were to measure...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2012-03-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/1734 |
| _version_ | 1797709676877447168 |
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| author | Gholam Hossein Ghafarpour Vahid Ebrahimi Mir Hadi Aziz Jalali |
| author_facet | Gholam Hossein Ghafarpour Vahid Ebrahimi Mir Hadi Aziz Jalali |
| author_sort | Gholam Hossein Ghafarpour |
| collection | DOAJ |
| description | Background: Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles. It is one of the most important skin disorders during adolescence. Zinc is one of essential trace elements in the body that has major roles in maintaining health. The main objectives of this study were to measure zinc serum levels and assess its relationship with age, sex, and disease severity in patients with acne vulgaris.
Methods: 100 consecutive patients with acne vulgaris referred to Hazrat-Rassoul-Akram hospital in 2010 were enrolled as a non-random sample. Fasting blood specimens were taken at 9 am and serum zinc level was measured by atomic absorption spectrophotometry method.
Findings: Mean serum zinc level of acne patients in this study was 106.78 ± 22.2 µg/dl. Mean levels of serum zinc were significantly lower in women compared to men (104.54 ± 2.72 µg/dl and 115.19 ±1.71 µg/dl, respectively; P < 0.05). There was no significant correlation between serum zinc and acne history or severity.
Conclusion: According to our findings, there is no link between serum zinc level and acne severity. Further evaluation of other contributing factors is suggested. |
| first_indexed | 2024-03-12T06:40:10Z |
| format | Article |
| id | doaj.art-713e5cf2649b4f3d939e831a18355934 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T06:40:10Z |
| publishDate | 2012-03-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-713e5cf2649b4f3d939e831a183559342023-09-03T01:02:58ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2012-03-0129173904The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris PatientsGholam Hossein Ghafarpour0Vahid Ebrahimi1Mir Hadi Aziz Jalali2Associate Professor, Skin and Stem Cell Research Center And Department of Dermatology, Hazrat Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran, IranResident, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan And Department of Dermatology, Hazrat Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran, IranAssociate Professor, Skin and Stem Cell Research Center And Department of Dermatology, Hazrat Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran, IranBackground: Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles. It is one of the most important skin disorders during adolescence. Zinc is one of essential trace elements in the body that has major roles in maintaining health. The main objectives of this study were to measure zinc serum levels and assess its relationship with age, sex, and disease severity in patients with acne vulgaris. Methods: 100 consecutive patients with acne vulgaris referred to Hazrat-Rassoul-Akram hospital in 2010 were enrolled as a non-random sample. Fasting blood specimens were taken at 9 am and serum zinc level was measured by atomic absorption spectrophotometry method. Findings: Mean serum zinc level of acne patients in this study was 106.78 ± 22.2 µg/dl. Mean levels of serum zinc were significantly lower in women compared to men (104.54 ± 2.72 µg/dl and 115.19 ±1.71 µg/dl, respectively; P < 0.05). There was no significant correlation between serum zinc and acne history or severity. Conclusion: According to our findings, there is no link between serum zinc level and acne severity. Further evaluation of other contributing factors is suggested.http://jims.mui.ac.ir/index.php/jims/article/view/1734ZincAcne vulgarisSeverity of illness |
| spellingShingle | Gholam Hossein Ghafarpour Vahid Ebrahimi Mir Hadi Aziz Jalali The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients مجله دانشکده پزشکی اصفهان Zinc Acne vulgaris Severity of illness |
| title | The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients |
| title_full | The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients |
| title_fullStr | The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients |
| title_full_unstemmed | The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients |
| title_short | The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients |
| title_sort | association of zinc serum level with age sex and disease severity in acne vulgaris patients |
| topic | Zinc Acne vulgaris Severity of illness |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/1734 |
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