Variation of DNA methylation on the IRX1/2 genes is responsible for the neural differentiation propensity in human induced pluripotent stem cells

Introduction: Human induced pluripotent stem cells (hiPSCs) are useful tools for reproducing neural development in vitro. However, each hiPSC line has a different ability to differentiate into specific lineages, known as differentiation propensity, resulting in reduced reproducibility and increased...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Asato Sekiya, Ken Takasawa, Yoshikazu Arai, Shin-ichi Horike, Hidenori Akutsu, Akihiro Umezawa, Koichiro Nishino
التنسيق: مقال
اللغة:English
منشور في: Elsevier 2022-12-01
سلاسل:Regenerative Therapy
الموضوعات:
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/S2352320422001122