IL-33 Is Involved in the Anti-Inflammatory Effects of Butyrate and Propionate on TNFα-Activated Endothelial Cells

IL-33 Is Involved in the Anti-Inflammatory Effects of Butyrate and Propionate on TNFα-Activated Endothelial Cells

Short-chain fatty acids (e.g., butyrate and propionate) are able to diminish endothelial cell activation. The aim of this study was to investigate whether intracellular IL-33 mediates the effects of butyrate and propionate on TNFα-induced IL-8 production and vascular cell adhesion molecule-1 (VCAM-1...

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Bibliographic Details
Main Authors:	Meng Li, Betty C. A. M. van Esch, Paul A. J. Henricks, Johan Garssen, Gert Folkerts
Format:	Article
Language:	English
Published:	MDPI AG 2021-02-01
Series:	International Journal of Molecular Sciences
Subjects:	short-chain fatty acids endothelial activation intracellular IL-33 HDACs NF-ĸB MAPK signaling pathways
Online Access:	https://www.mdpi.com/1422-0067/22/5/2447

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