GOLPH3 Participates in Mitochondrial Fission and Is Necessary to Sustain Bioenergetic Function in MDA-MB-231 Breast Cancer Cells

GOLPH3 Participates in Mitochondrial Fission and Is Necessary to Sustain Bioenergetic Function in MDA-MB-231 Breast Cancer Cells

In this study, we investigated the inter-organelle communication between the Golgi apparatus (GA) and mitochondria. Previous observations suggest that GA-derived vesicles containing phosphatidylinositol 4-phosphate (PI(4)P) play a role in mitochondrial fission, colocalizing with DRP1, a key protein...

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Bibliographic Details
Main Authors: Catalina M. Polanco, Viviana A. Cavieres, Abigail J. Galarza, Claudia Jara, Angie K. Torres, Jorge Cancino, Manuel Varas-Godoy, Patricia V. Burgos, Cheril Tapia-Rojas, Gonzalo A. Mardones
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
GOLPH3
PI(4)P
DRP1
mitochondrial bioenergetics
mitochondrial fission and fusion
mitochondrial fragmentation
Online Access:https://www.mdpi.com/2073-4409/13/4/316

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