MATCHER: manifold alignment reveals correspondence between single cell transcriptome and epigenome dynamics
Abstract Single cell experimental techniques reveal transcriptomic and epigenetic heterogeneity among cells, but how these are related is unclear. We present MATCHER, an approach for integrating multiple types of single cell measurements. MATCHER uses manifold alignment to infer single cell multi-om...
Main Authors: | Joshua D. Welch, Alexander J. Hartemink, Jan F. Prins |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-07-01
|
Series: | Genome Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13059-017-1269-0 |
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