EIF4A3-induced circular RNA PRKAR1B promotes osteosarcoma progression by miR-361-3p-mediated induction of FZD4 expression

Abstract Emerging evidence indicates that circRNAs are broadly expressed in osteosarcoma (OS) cells and play a crucial role in OS progression. Recently, cancer-specific circRNA circPRKAR1B has been identified by high-throughput sequencing and is recorded in publicly available databases. Nevertheless...

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Bibliographic Details
Main Authors: Zhen-hua Feng, Lin Zheng, Teng Yao, Si-yue Tao, Xiao-an Wei, Ze-yu Zheng, Bing-jie Zheng, Xu-yang Zhang, Bao Huang, Jun-hui Liu, Yi-lei Chen, Zhi Shan, Pu-tao Yuan, Cheng-gui Wang, Jian Chen, Shu-ying Shen, Feng-dong Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04339-7