Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review
Biological sex plays an important role in normal cardiac physiology as well as in the heart‘s response to cardiac disease. Women generally have better cardiac function and survival than do men in the face of cardiac disease; however, this is progressively lost when comparing postmenopausal women w...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2014-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/4771/9635_CE(Ra)_F(Sh)_PF1(PAK)_PFA(AK).pdf |
| _version_ | 1818148162656796672 |
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| author | K.Prabhavathi K.Tamarai Selvi K.N.Poornima A.Sarvanan |
| author_facet | K.Prabhavathi K.Tamarai Selvi K.N.Poornima A.Sarvanan |
| author_sort | K.Prabhavathi |
| collection | DOAJ |
| description | Biological sex plays an important role in normal cardiac physiology as well as in the heart‘s response to cardiac disease. Women generally
have better cardiac function and survival than do men in the face of cardiac disease; however, this is progressively lost when comparing
postmenopausal women with age matched men. Animal model of cardiac disease mirror what is seen in humans. Sex hormones contribute
significantly to sex based difference in cardiac functioning and in its disease outcome. Estrogen is considered to be cardioprotective,
whereas testosterone is detrimental to heart function. |
| first_indexed | 2024-12-11T12:46:46Z |
| format | Article |
| id | doaj.art-714bc95cae934c7885a3986397df2676 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T12:46:46Z |
| publishDate | 2014-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-714bc95cae934c7885a3986397df26762022-12-22T01:06:48ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-08-0188BE01BE0410.7860/JCDR/2014/9635.4771Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A ReviewK.Prabhavathi0K.Tamarai Selvi1K.N.Poornima2A.Sarvanan3Assistant Professor, Department of Physiology, SRM Medical College and Research Center, Chennai, Tamil Nadu, India.Professor, Department of Physiology, SRM Medical College and Research Center, Chennai, Tamil Nadu, India.Tutor, Department of Physiology, SRM Medical College and Research Center, Chennai, Tamil Nadu, India.Professor, Department of Physiology, SRM Medical College and Research Center, Chennai, Tamil Nadu, India.Biological sex plays an important role in normal cardiac physiology as well as in the heart‘s response to cardiac disease. Women generally have better cardiac function and survival than do men in the face of cardiac disease; however, this is progressively lost when comparing postmenopausal women with age matched men. Animal model of cardiac disease mirror what is seen in humans. Sex hormones contribute significantly to sex based difference in cardiac functioning and in its disease outcome. Estrogen is considered to be cardioprotective, whereas testosterone is detrimental to heart function.https://jcdr.net/articles/PDF/4771/9635_CE(Ra)_F(Sh)_PF1(PAK)_PFA(AK).pdfestrogengendertestosterone |
| spellingShingle | K.Prabhavathi K.Tamarai Selvi K.N.Poornima A.Sarvanan Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review Journal of Clinical and Diagnostic Research estrogen gender testosterone |
| title | Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review |
| title_full | Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review |
| title_fullStr | Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review |
| title_full_unstemmed | Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review |
| title_short | Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome – A Review |
| title_sort | role of biological sex in normal cardiac function and in its disease outcome a review |
| topic | estrogen gender testosterone |
| url | https://jcdr.net/articles/PDF/4771/9635_CE(Ra)_F(Sh)_PF1(PAK)_PFA(AK).pdf |
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