GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior

GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior

Abstract Many neurotransmitters directly inhibit neurons by activating G protein-gated inwardly rectifying K+ (GIRK) channels, thereby moderating the influence of excitatory input on neuronal excitability. While most neuronal GIRK channels are formed by GIRK1 and GIRK2 subunits, distinct GIRK2 isofo...

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Bibliographic Details
Main Authors: Ezequiel Marron Fernandez de Velasco, Lei Zhang, Baovi N. Vo, Megan Tipps, Shannon Farris, Zhilian Xia, Allison Anderson, Nicholas Carlblom, C. David Weaver, Serena M. Dudek, Kevin Wickman
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01820-2

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