SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions

SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions

This paper presents a molecular characterization of the interaction between the SARS-CoV-2 envelope (E) protein and TLR2. We demonstrated that the E protein, both as a recombinant soluble protein and as a native membrane protein associated with SARS-CoV-2 viral particles, interacts physically with t...

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Bibliographic Details
Main Authors: Rémi Planès, Jean-Baptiste Bert, Sofiane Tairi, Lbachir BenMohamed, Elmostafa Bahraoui
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
SARS-CoV-2
envelop (E) protein
TLR2
CXCL8
Online Access:https://www.mdpi.com/1999-4915/14/5/999

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