Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block
Introduction: Supraclavicular brachial plexus block is a commonly used, reliable regional anaesthetic technique for surgery of the upper limb. An adjuvant such as fentanyl/ Nalbuphine is used to prolong the effect of bupivacaine. Aim: To evaluate the efficacy of adding fentanyl/nalbuphine as an adju...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2019-03-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/12699/40042_CE[Ra1]_F(AC)_PF1(AJ_SHU)_PFA(AJ_KM_SHU)_GC(SU_SL)_PN(SL).pdf |
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| author | Rajesh Kumar Ajay Kumar Chaudhary Hemlata Reetu Verma Radhey Shyam Vipin Kumar Singh |
| author_facet | Rajesh Kumar Ajay Kumar Chaudhary Hemlata Reetu Verma Radhey Shyam Vipin Kumar Singh |
| author_sort | Rajesh Kumar |
| collection | DOAJ |
| description | Introduction: Supraclavicular brachial plexus block is a commonly used, reliable regional anaesthetic technique for surgery of the upper limb. An adjuvant such as fentanyl/ Nalbuphine is used to prolong the effect of bupivacaine. Aim: To evaluate the efficacy of adding fentanyl/nalbuphine as an adjuvant to bupivacaine in Ultrasound (US) guided supraclavicular brachial plexus blockade. Materials and Methods: A total 60 ASA I and II adult patients undergoing upper limb surgeries were randomly allocated to two groups. Group A received 20 mL of 0.5% bupivacaine with 2 mL fentanyl 100 µgm with 10 mL of normal saline and Group B received 20 mL of 0.5% bupivacaine with 2 mL of nalbuphine 20 mg with 10 mL Normal Saline (NS) for supraclavicular brachial plexus blockade. The two groups were compared for the time of onset, duration of sensory and motor blocks, hemodynamic stability, post-operative analgesia and complications. Student’s t-test, chi-square test, and Mann-Whitney U-test were used for statistical analysis. Results: The onset time of sensory block (12.07±1.08 and 8.20±1.32 minutes) and motor block (16.80±1.27 and 14.03±1.22 minutes) were significantly different in between Group A and Group B. The duration of sensory block (466.87±39.84 and 719.23±19.45 minutes) and motor block (16.80±1.27 and 14.03±1.22 minutes) were significantly different in between Group A and Group B. The duration (min.) of analgesia was significantly different between Group A (660.67±31.77) and Group B (836.13±25.74). Conclusion: Nalbuphine 20 mg significantly prolongs the duration of analgesia of supraclavicular brachial plexus block as compared to fentanyl group. |
| first_indexed | 2024-12-11T17:35:44Z |
| format | Article |
| id | doaj.art-715bb376c5ac4a03aa17b31ed5af8d01 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T17:35:44Z |
| publishDate | 2019-03-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-715bb376c5ac4a03aa17b31ed5af8d012022-12-22T00:56:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2019-03-01133UC06UC1010.7860/JCDR/2019/40042.12699Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus BlockRajesh Kumar0Ajay Kumar Chaudhary1Hemlata2Reetu Verma3Radhey Shyam4Vipin Kumar Singh5Junior Resident, Department of Anaesthesiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.Professor, Department of Anaesthesiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.Assistant Professor, Department of Anaesthesiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.Associate Professor, Department of Anaesthesiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.Associate Professor, Department of Anaesthesiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.Assistant Professor, Department of Anaesthesiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.Introduction: Supraclavicular brachial plexus block is a commonly used, reliable regional anaesthetic technique for surgery of the upper limb. An adjuvant such as fentanyl/ Nalbuphine is used to prolong the effect of bupivacaine. Aim: To evaluate the efficacy of adding fentanyl/nalbuphine as an adjuvant to bupivacaine in Ultrasound (US) guided supraclavicular brachial plexus blockade. Materials and Methods: A total 60 ASA I and II adult patients undergoing upper limb surgeries were randomly allocated to two groups. Group A received 20 mL of 0.5% bupivacaine with 2 mL fentanyl 100 µgm with 10 mL of normal saline and Group B received 20 mL of 0.5% bupivacaine with 2 mL of nalbuphine 20 mg with 10 mL Normal Saline (NS) for supraclavicular brachial plexus blockade. The two groups were compared for the time of onset, duration of sensory and motor blocks, hemodynamic stability, post-operative analgesia and complications. Student’s t-test, chi-square test, and Mann-Whitney U-test were used for statistical analysis. Results: The onset time of sensory block (12.07±1.08 and 8.20±1.32 minutes) and motor block (16.80±1.27 and 14.03±1.22 minutes) were significantly different in between Group A and Group B. The duration of sensory block (466.87±39.84 and 719.23±19.45 minutes) and motor block (16.80±1.27 and 14.03±1.22 minutes) were significantly different in between Group A and Group B. The duration (min.) of analgesia was significantly different between Group A (660.67±31.77) and Group B (836.13±25.74). Conclusion: Nalbuphine 20 mg significantly prolongs the duration of analgesia of supraclavicular brachial plexus block as compared to fentanyl group.https://jcdr.net/articles/PDF/12699/40042_CE[Ra1]_F(AC)_PF1(AJ_SHU)_PFA(AJ_KM_SHU)_GC(SU_SL)_PN(SL).pdfhaemodynamiclimb surgerieslocal anaesthesiapostoperative analgesia |
| spellingShingle | Rajesh Kumar Ajay Kumar Chaudhary Hemlata Reetu Verma Radhey Shyam Vipin Kumar Singh Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block Journal of Clinical and Diagnostic Research haemodynamic limb surgeries local anaesthesia postoperative analgesia |
| title | Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block |
| title_full | Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block |
| title_fullStr | Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block |
| title_full_unstemmed | Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block |
| title_short | Comparison of Fentanyl and Nalbuphine as an Adjuvant to 0.5% Bupivacaine for Ultrasound Guided Supraclavicular Brachial Plexus Block |
| title_sort | comparison of fentanyl and nalbuphine as an adjuvant to 0 5 bupivacaine for ultrasound guided supraclavicular brachial plexus block |
| topic | haemodynamic limb surgeries local anaesthesia postoperative analgesia |
| url | https://jcdr.net/articles/PDF/12699/40042_CE[Ra1]_F(AC)_PF1(AJ_SHU)_PFA(AJ_KM_SHU)_GC(SU_SL)_PN(SL).pdf |
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