The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase

The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase

<p>Abstract</p> <p>Background</p> <p>The activity of the ribonucleoprotein enzyme telomerase is detectable in germ, stem and tumor cells. One major component of telomerase is human telomerase reverse transcriptase (hTERT), which encodes the catalytic subunit of telomera...

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Bibliographic Details
Main Authors: Schulze Wolfgang, Schostak Martin, Straub Bernd, Krause Hans, Müller Markus, Burger Angelika M, Schrader Mark, Lauke Heidrun, Miller Kurt
Format: Article
Language:English
Published: BMC 2002-11-01
Series:BMC Cancer
Subjects:
Telomerase activity
human telomerase reverse transcriptase
testicular germ cell tumors
Online Access:http://www.biomedcentral.com/1471-2407/2/32

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