Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case

The topical diagnosis of insulinoma continues to be an actual problem of modern medicine due to low detection rate of the tumor (about 75%) and inconsistent data on its localization when using various methods of visualization (more than in 50% of cases), as well as the lack of a single diagnostic al...

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Main Authors: M. Yu. Yukina, N. F. Nuralieva, E. A. Troshina, A. V. Vorontsov, V. P. Vladimirova, T. V. Soldatova, N. S. Kuznetsov, N. V. Latkina, N. S. Izmaylova
Format: Article
Language:Russian
Published: MONIKI 2018-08-01
Series:Alʹmanah Kliničeskoj Mediciny
Subjects:
Online Access:https://www.almclinmed.ru/jour/article/view/832
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author M. Yu. Yukina
N. F. Nuralieva
E. A. Troshina
A. V. Vorontsov
V. P. Vladimirova
T. V. Soldatova
N. S. Kuznetsov
N. V. Latkina
N. S. Izmaylova
author_facet M. Yu. Yukina
N. F. Nuralieva
E. A. Troshina
A. V. Vorontsov
V. P. Vladimirova
T. V. Soldatova
N. S. Kuznetsov
N. V. Latkina
N. S. Izmaylova
author_sort M. Yu. Yukina
collection DOAJ
description The topical diagnosis of insulinoma continues to be an actual problem of modern medicine due to low detection rate of the tumor (about 75%) and inconsistent data on its localization when using various methods of visualization (more than in 50% of cases), as well as the lack of a single diagnostic algorithm. In the clinical practice, many different imaging assessments are conducted, including those with the administration of contrast agents and associated with radiation load, as well as invasive studies, associated with risk of various complications, high costs and duration of the examination. Thus, the search for highly sensitive and safe methods of topical diagnosis of the insulin-producing pancreatic tumor seems relevant. In the presented clinical case, the diagnosis of insulinoma is verified by diffusion-weighted magnetic resonance imaging (DW-MRI). It is an accurate and non-invasive method that does not involve exposure to ionizing radiation and does not require any administration of contrast agents. This technology, based on microstructural pathological changes, allows to identify small tumors and to make a differential diagnosis of benign and malignant neoplasms. However, at present the experience of DW-MRI use for the diagnosis of an insulin-producing neuroendocrine tumor is limited. Evaluation of its effectiveness in a large patient cohort would be necessary to assess the prospects for its introduction into clinical practice.
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spelling doaj.art-7162fe861c0f4a7196af2483cb90ff662022-12-21T18:23:15ZrusMONIKIAlʹmanah Kliničeskoj Mediciny2072-05052587-92942018-08-0146328929510.18786/2072-0505-2018-46-3-289-295542Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical caseM. Yu. Yukina0N. F. Nuralieva1E. A. Troshina2A. V. Vorontsov3V. P. Vladimirova4T. V. Soldatova5N. S. Kuznetsov6N. V. Latkina7N. S. Izmaylova8Endocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterEndocrinology Research CenterThe topical diagnosis of insulinoma continues to be an actual problem of modern medicine due to low detection rate of the tumor (about 75%) and inconsistent data on its localization when using various methods of visualization (more than in 50% of cases), as well as the lack of a single diagnostic algorithm. In the clinical practice, many different imaging assessments are conducted, including those with the administration of contrast agents and associated with radiation load, as well as invasive studies, associated with risk of various complications, high costs and duration of the examination. Thus, the search for highly sensitive and safe methods of topical diagnosis of the insulin-producing pancreatic tumor seems relevant. In the presented clinical case, the diagnosis of insulinoma is verified by diffusion-weighted magnetic resonance imaging (DW-MRI). It is an accurate and non-invasive method that does not involve exposure to ionizing radiation and does not require any administration of contrast agents. This technology, based on microstructural pathological changes, allows to identify small tumors and to make a differential diagnosis of benign and malignant neoplasms. However, at present the experience of DW-MRI use for the diagnosis of an insulin-producing neuroendocrine tumor is limited. Evaluation of its effectiveness in a large patient cohort would be necessary to assess the prospects for its introduction into clinical practice.https://www.almclinmed.ru/jour/article/view/832insulinomatopical diagnosisdiffusion-weighted magnetic resonance imaging
spellingShingle M. Yu. Yukina
N. F. Nuralieva
E. A. Troshina
A. V. Vorontsov
V. P. Vladimirova
T. V. Soldatova
N. S. Kuznetsov
N. V. Latkina
N. S. Izmaylova
Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case
Alʹmanah Kliničeskoj Mediciny
insulinoma
topical diagnosis
diffusion-weighted magnetic resonance imaging
title Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case
title_full Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case
title_fullStr Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case
title_full_unstemmed Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case
title_short Diffusion-weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma: a clinical case
title_sort diffusion weighted magnetic resonance imaging in the diagnosis of pancreatic insulinoma a clinical case
topic insulinoma
topical diagnosis
diffusion-weighted magnetic resonance imaging
url https://www.almclinmed.ru/jour/article/view/832
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