Lower urinary tract signs and symptoms in patients with COVID-19
Abstract Background The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms. Methods The effect of COVID-19 on lower urinary tract function was studied in a...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-07-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-021-06394-z |
| _version_ | 1818695988731183104 |
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| author | Aida Javan Balegh Marand Christian Bach Dick Janssen John Heesakkers Morteza Ghojazadeh Thomas Alexander Vögeli Hanieh Salehi-Pourmehr Hadi Mostafae Sakineh Hajebrahimi Mohammad Sajjad Rahnama’i |
| author_facet | Aida Javan Balegh Marand Christian Bach Dick Janssen John Heesakkers Morteza Ghojazadeh Thomas Alexander Vögeli Hanieh Salehi-Pourmehr Hadi Mostafae Sakineh Hajebrahimi Mohammad Sajjad Rahnama’i |
| author_sort | Aida Javan Balegh Marand |
| collection | DOAJ |
| description | Abstract Background The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms. Methods The effect of COVID-19 on lower urinary tract function was studied in a prospective multi-centre, observational study including 238 patients who were admitted with symptoms caused by COVID-19 to the university hospital of Aachen in Germany and Tabriz in Iran. Results None of the patients reported to have any lower urinary tract symptoms. SARS-CoV-2 was found in the urine of 19% of the tested patients. The mortality rate in COVID-19 infected patients with microscopic haematuria together with white blood cells in their urine, was significantly increased from 48 to 61% in the Tabriz cohort (p-value = 0.03) and from 30 to 35% in the Aachen cohort (p-value =0.045). Furthermore, in the group of patients with SARS-CoV-2 urine PCR, the mortality rate rose from 30 to 58%. (p-value =0.039). Conclusion Patients admitted with COVID-19 did not report to have any lower urinary tract symptoms, even those patient who had a positive Urine SARS-CoV-2 PCR. In addition, hematuria, WBC in urine as well as SARS- CoV-2 presence in urine, were found to be strong negative prognostic factors in admitted COVID-19 patients. |
| first_indexed | 2024-12-17T13:54:13Z |
| format | Article |
| id | doaj.art-716350ea86874a869d84b1713c43c990 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-17T13:54:13Z |
| publishDate | 2021-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-716350ea86874a869d84b1713c43c9902022-12-21T21:45:59ZengBMCBMC Infectious Diseases1471-23342021-07-012111510.1186/s12879-021-06394-zLower urinary tract signs and symptoms in patients with COVID-19Aida Javan Balegh Marand0Christian Bach1Dick Janssen2John Heesakkers3Morteza Ghojazadeh4Thomas Alexander Vögeli5Hanieh Salehi-Pourmehr6Hadi Mostafae7Sakineh Hajebrahimi8Mohammad Sajjad Rahnama’i9Uniklinik RWTH AachenUniklinik RWTH AachenRadboud UniversityRadboud UniversityResearch Center for Evidence-Based Medicine, Tabriz University of Medical SciencesUniklinik RWTH AachenResearch Center for Evidence-Based Medicine, Tabriz University of Medical SciencesMedical University of ViennaResearch Center for Evidence-Based Medicine, Tabriz University of Medical SciencesUniklinik RWTH AachenAbstract Background The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms. Methods The effect of COVID-19 on lower urinary tract function was studied in a prospective multi-centre, observational study including 238 patients who were admitted with symptoms caused by COVID-19 to the university hospital of Aachen in Germany and Tabriz in Iran. Results None of the patients reported to have any lower urinary tract symptoms. SARS-CoV-2 was found in the urine of 19% of the tested patients. The mortality rate in COVID-19 infected patients with microscopic haematuria together with white blood cells in their urine, was significantly increased from 48 to 61% in the Tabriz cohort (p-value = 0.03) and from 30 to 35% in the Aachen cohort (p-value =0.045). Furthermore, in the group of patients with SARS-CoV-2 urine PCR, the mortality rate rose from 30 to 58%. (p-value =0.039). Conclusion Patients admitted with COVID-19 did not report to have any lower urinary tract symptoms, even those patient who had a positive Urine SARS-CoV-2 PCR. In addition, hematuria, WBC in urine as well as SARS- CoV-2 presence in urine, were found to be strong negative prognostic factors in admitted COVID-19 patients.https://doi.org/10.1186/s12879-021-06394-zLower urinary tract symptoms (LUTS)COVID-19SARS-CoV-2HematuriaUrine, leukocyturia |
| spellingShingle | Aida Javan Balegh Marand Christian Bach Dick Janssen John Heesakkers Morteza Ghojazadeh Thomas Alexander Vögeli Hanieh Salehi-Pourmehr Hadi Mostafae Sakineh Hajebrahimi Mohammad Sajjad Rahnama’i Lower urinary tract signs and symptoms in patients with COVID-19 BMC Infectious Diseases Lower urinary tract symptoms (LUTS) COVID-19 SARS-CoV-2 Hematuria Urine, leukocyturia |
| title | Lower urinary tract signs and symptoms in patients with COVID-19 |
| title_full | Lower urinary tract signs and symptoms in patients with COVID-19 |
| title_fullStr | Lower urinary tract signs and symptoms in patients with COVID-19 |
| title_full_unstemmed | Lower urinary tract signs and symptoms in patients with COVID-19 |
| title_short | Lower urinary tract signs and symptoms in patients with COVID-19 |
| title_sort | lower urinary tract signs and symptoms in patients with covid 19 |
| topic | Lower urinary tract symptoms (LUTS) COVID-19 SARS-CoV-2 Hematuria Urine, leukocyturia |
| url | https://doi.org/10.1186/s12879-021-06394-z |
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