Relationship between Sleep, Pain and Inflammatory Markers in Patients with Rheumatoid Arthritis
Introduction: Rheumatoid Arthritis (RA) is known as a progressive chronic auto-immune disease. Measurement of inflammatory markers are applied for follow up the activity of disease. So determining factors that effects these markers such as sleep and pain can help to prevent the sev...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2017-09-01
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| Series: | Journal of Caring Sciences |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/JCS/Manuscript/JCS-6-249.pdf |
| _version_ | 1819102596536729600 |
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| author | Majid Purabdollah Sima lakdizaji Azad Rahmani |
| author_facet | Majid Purabdollah Sima lakdizaji Azad Rahmani |
| author_sort | Majid Purabdollah |
| collection | DOAJ |
| description | Introduction: Rheumatoid Arthritis (RA) is known as a progressive
chronic auto-immune disease. Measurement of inflammatory markers are applied for follow up the
activity of disease. So determining factors that effects these markers such as sleep and pain
can help to prevent the severity of disease. The aim of study was to determine the
relationship between sleep disorders, pain and inflammatory markers in patients with RA.
Methods: Participants included 210 patients with RA referred to educational medical clinics of
Imam Reza and Sina in Tabriz selected by convenience sampling. They were assessed by Sleep
Disorders Questionnaire (SDQ) and Epworth Sleepiness Scale (ESS). Visual Analog Scale (VAS)
also applied for pain measurement. Data were analyzed using SPSS ver.13 by descriptive and
inferential statistics. Results: Most of participants (74%) were female, the mean age of
participants was 48.41 years. The mean (SD) of sleepiness was 13.14 (5.6) and pain 6.09
(2.14). Significant relationship obtained between sleep disorders and pain. As well as sleep
problems had significant relation with CRP. Also pain had significant correlation with
inflammatory markers. Conclusion: Sleep pattern in RA appears to be disrupted by pain. Pain
severity and sleep problems can predict increasing inflammatory markers that can be a clues of
intensity of disease. So relieving pain and improved sleep can decrease the intensity of
disease. |
| first_indexed | 2024-12-22T01:37:05Z |
| format | Article |
| id | doaj.art-7169273d64224a5b8cd631bfba92bc25 |
| institution | Directory Open Access Journal |
| issn | 2251-9920 |
| language | English |
| last_indexed | 2024-12-22T01:37:05Z |
| publishDate | 2017-09-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Caring Sciences |
| spelling | doaj.art-7169273d64224a5b8cd631bfba92bc252022-12-21T18:43:20ZengTabriz University of Medical SciencesJournal of Caring Sciences2251-99202017-09-016324925510.15171/jcs.2017.024JCS_32_20170312202915Relationship between Sleep, Pain and Inflammatory Markers in Patients with Rheumatoid ArthritisMajid Purabdollah0Sima lakdizaji1Azad Rahmani2Medical Surgical Nursing Department, Nursing and Midwifery Faculty, Tabriz University of Medical Science, Tabriz, Iran Medical Surgical Nursing Department, Nursing and Midwifery Faculty, Tabriz University of Medical Science, Tabriz, Iran Medical Surgical Nursing Department, Nursing and Midwifery Faculty, Tabriz University of Medical Science, Tabriz, Iran Introduction: Rheumatoid Arthritis (RA) is known as a progressive chronic auto-immune disease. Measurement of inflammatory markers are applied for follow up the activity of disease. So determining factors that effects these markers such as sleep and pain can help to prevent the severity of disease. The aim of study was to determine the relationship between sleep disorders, pain and inflammatory markers in patients with RA. Methods: Participants included 210 patients with RA referred to educational medical clinics of Imam Reza and Sina in Tabriz selected by convenience sampling. They were assessed by Sleep Disorders Questionnaire (SDQ) and Epworth Sleepiness Scale (ESS). Visual Analog Scale (VAS) also applied for pain measurement. Data were analyzed using SPSS ver.13 by descriptive and inferential statistics. Results: Most of participants (74%) were female, the mean age of participants was 48.41 years. The mean (SD) of sleepiness was 13.14 (5.6) and pain 6.09 (2.14). Significant relationship obtained between sleep disorders and pain. As well as sleep problems had significant relation with CRP. Also pain had significant correlation with inflammatory markers. Conclusion: Sleep pattern in RA appears to be disrupted by pain. Pain severity and sleep problems can predict increasing inflammatory markers that can be a clues of intensity of disease. So relieving pain and improved sleep can decrease the intensity of disease.http://journals.tbzmed.ac.ir/JCS/Manuscript/JCS-6-249.pdfArthritis rheumatoidDisordersInflammationC-reactive protein |
| spellingShingle | Majid Purabdollah Sima lakdizaji Azad Rahmani Relationship between Sleep, Pain and Inflammatory Markers in Patients with Rheumatoid Arthritis Journal of Caring Sciences Arthritis rheumatoid Disorders Inflammation C-reactive protein |
| title | Relationship between Sleep, Pain and Inflammatory Markers in Patients with
Rheumatoid Arthritis |
| title_full | Relationship between Sleep, Pain and Inflammatory Markers in Patients with
Rheumatoid Arthritis |
| title_fullStr | Relationship between Sleep, Pain and Inflammatory Markers in Patients with
Rheumatoid Arthritis |
| title_full_unstemmed | Relationship between Sleep, Pain and Inflammatory Markers in Patients with
Rheumatoid Arthritis |
| title_short | Relationship between Sleep, Pain and Inflammatory Markers in Patients with
Rheumatoid Arthritis |
| title_sort | relationship between sleep pain and inflammatory markers in patients with rheumatoid arthritis |
| topic | Arthritis rheumatoid Disorders Inflammation C-reactive protein |
| url | http://journals.tbzmed.ac.ir/JCS/Manuscript/JCS-6-249.pdf |
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