Radiation Type- and Dose-Specific Transcriptional Responses across Healthy and Diseased Mammalian Tissues

Radiation Type- and Dose-Specific Transcriptional Responses across Healthy and Diseased Mammalian Tissues

Ionizing radiation (IR) is a genuine genotoxic agent and a major modality in cancer treatment. IR disrupts DNA sequences and exerts mutagenic and/or cytotoxic properties that not only alter critical cellular functions but also impact tissues proximal and distal to the irradiated site. Unveiling the...

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Bibliographic Details
Main Authors: Eftychia Sagkrioti, Gökay Mehmet Biz, Işıl Takan, Seyedehsadaf Asfa, Zacharenia Nikitaki, Vassiliki Zanni, Rumeysa Hanife Kars, Christine E. Hellweg, Edouard I. Azzam, Stella Logotheti, Athanasia Pavlopoulou, Alexandros G. Georgakilas
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
radiation response
bioinformatics
oxidative stress
transcriptomics
radiobiology database
gene signature
Online Access:https://www.mdpi.com/2076-3921/11/11/2286

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