The role of thrombin in early-onset seizures

The role of thrombin in early-onset seizures

A variety of clinical observations and studies in animal models of temporal lobe epilepsy (TLE) reveal dysfunction of blood-brain barrier (BBB) during seizures. It is accompanied by shifts in ionic composition, imbalance in transmitters and metabolic products, extravasation of blood plasma proteins...

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Bibliographic Details
Main Authors:	Alina Savotchenko, Mariia Klymenko, Mariia Shypshyna, Dmytro Isaev
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	thrombin blood-brain barrier hippocampus status epilepticus temporal-lobe epilepsy lithium-pilocarpine model
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2023.1101006/full

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