Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy
ABSTRACTPurpose To explore the value of magnetic resonance imaging (MRI) T2 mapping combined with susceptibility-weighted imaging (SWI) in detecting early cartilage damage and joint bleeding in the hemophilic arthropathy (HA).Methods 147 patients and 56 healthy controls were prospectively recruited....
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Taylor & Francis Group
2022-12-01
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| Series: | Hematology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/16078454.2022.2147316 |
| _version_ | 1811311729189060608 |
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| author | Lu Zhang Shufang Wei Jiajia Li Pengming Wang Ge Yinghui |
| author_facet | Lu Zhang Shufang Wei Jiajia Li Pengming Wang Ge Yinghui |
| author_sort | Lu Zhang |
| collection | DOAJ |
| description | ABSTRACTPurpose To explore the value of magnetic resonance imaging (MRI) T2 mapping combined with susceptibility-weighted imaging (SWI) in detecting early cartilage damage and joint bleeding in the hemophilic arthropathy (HA).Methods 147 patients and 56 healthy controls were prospectively recruited. The knees were divided into groups A and B according to the criteria of the International Cartilage Repair Society (ICRS). The Regions of Interest (ROIs) of T2 mapping were drawn for the patella, lateral and medial femoral condyle, and lateral and medial tibial condyle. The T2 values were compared between the patients and control group using one-way ANOVA. The joint count data of International Prophylaxis Study Group (IPSG) scores of conventional and SWI sequences were statistically described using the composition ratio, and the rank sum test was used for the difference analysis.Results Finally, there were 99 joints in the control group, 135 knees in group A, and 94 knees in group B. There was a significant difference between the T2 value in each subgroup. Comparison of T2 value groups in each cartilage partition, except for group A and group B of the patella, revealed significant differences (all P<0.05). SWI was likely more sensitive than conventional sequences in detecting hemosiderin deposits in hemophilic joints. In addition, the IPSG scores detected by the SWI were generally higher than those of conventional sequences.Conclusions MR T2 mapping combined with SWI has great potential to be used for detecting early cartilage damage and micro-hemosiderin deposition in hemophiliac arthropathies and developing preventative treatment plans. |
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| id | doaj.art-7174a0389c734e6cb5fbd6a7d889e9e6 |
| institution | Directory Open Access Journal |
| issn | 1607-8454 |
| language | English |
| last_indexed | 2024-04-13T10:23:59Z |
| publishDate | 2022-12-01 |
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| series | Hematology |
| spelling | doaj.art-7174a0389c734e6cb5fbd6a7d889e9e62022-12-22T02:50:22ZengTaylor & Francis GroupHematology1607-84542022-12-012711263127110.1080/16078454.2022.2147316Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathyLu Zhang0Shufang Wei1Jiajia Li2Pengming Wang3Ge Yinghui4Department of Medical Imaging, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, People’s Republic of ChinaDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Zhengzhou, People’s Republic of ChinaDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Zhengzhou, People’s Republic of ChinaDepartment of Radiology, The First Affiliated Hospital of Xinxiang Medical College, Xinxiang, People’s Republic of ChinaDepartment of Medical Imaging, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, People’s Republic of ChinaABSTRACTPurpose To explore the value of magnetic resonance imaging (MRI) T2 mapping combined with susceptibility-weighted imaging (SWI) in detecting early cartilage damage and joint bleeding in the hemophilic arthropathy (HA).Methods 147 patients and 56 healthy controls were prospectively recruited. The knees were divided into groups A and B according to the criteria of the International Cartilage Repair Society (ICRS). The Regions of Interest (ROIs) of T2 mapping were drawn for the patella, lateral and medial femoral condyle, and lateral and medial tibial condyle. The T2 values were compared between the patients and control group using one-way ANOVA. The joint count data of International Prophylaxis Study Group (IPSG) scores of conventional and SWI sequences were statistically described using the composition ratio, and the rank sum test was used for the difference analysis.Results Finally, there were 99 joints in the control group, 135 knees in group A, and 94 knees in group B. There was a significant difference between the T2 value in each subgroup. Comparison of T2 value groups in each cartilage partition, except for group A and group B of the patella, revealed significant differences (all P<0.05). SWI was likely more sensitive than conventional sequences in detecting hemosiderin deposits in hemophilic joints. In addition, the IPSG scores detected by the SWI were generally higher than those of conventional sequences.Conclusions MR T2 mapping combined with SWI has great potential to be used for detecting early cartilage damage and micro-hemosiderin deposition in hemophiliac arthropathies and developing preventative treatment plans.https://www.tandfonline.com/doi/10.1080/16078454.2022.2147316Articular cartilagehemophilic arthropathymagnetic resonance imagingT2mappingSWI |
| spellingShingle | Lu Zhang Shufang Wei Jiajia Li Pengming Wang Ge Yinghui Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy Hematology Articular cartilage hemophilic arthropathy magnetic resonance imaging T2mapping SWI |
| title | Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy |
| title_full | Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy |
| title_fullStr | Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy |
| title_full_unstemmed | Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy |
| title_short | Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy |
| title_sort | value of 3 0t mri t2 mapping combined with swi for the assessment of early lesions in hemophilic arthropathy |
| topic | Articular cartilage hemophilic arthropathy magnetic resonance imaging T2mapping SWI |
| url | https://www.tandfonline.com/doi/10.1080/16078454.2022.2147316 |
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