KS23, a novel peptide derived from adiponectin, inhibits retinal inflammation and downregulates the proportions of Th1 and Th17 cells during experimental autoimmune uveitis

KS23, a novel peptide derived from adiponectin, inhibits retinal inflammation and downregulates the proportions of Th1 and Th17 cells during experimental autoimmune uveitis

Abstract Background Uveitis is a potentially sight-threatening form of ocular inflammation that affects the uvea in the wall of the eye. Currently available treatments for uveitis have exhibited profound adverse side effects. However, KS23 is a novel 23-amino-acid anti-inflammatory peptide derived f...

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Bibliographic Details
Main Authors: Tian Niu, Lu Cheng, Hanying Wang, Shaopin Zhu, Xiaolu Yang, Kun Liu, Huiyi Jin, Xun Xu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Neuroinflammation
Subjects:
Experimental autoimmune uveitis
KS23
Adiponectin
AMPK
Th17 cells
Peptide
Online Access:https://doi.org/10.1186/s12974-019-1686-y

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