Diet-induced obesity reduces bone marrow T and B cells and promotes tumor progression in a transplantable Vk*MYC model of multiple myeloma

Diet-induced obesity reduces bone marrow T and B cells and promotes tumor progression in a transplantable Vk*MYC model of multiple myeloma

Abstract Obesity is associated with an increased risk of developing multiple myeloma (MM). The molecular mechanisms causing this association is complex and incompletely understood. Whether obesity affects bone marrow immune cell composition in multiple myeloma is not characterized. Here, we examined...

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Bibliographic Details
Main Authors: Tonje Marie Vikene Nedal, Siv Helen Moen, Ingrid Aass Roseth, Synne Stokke Tryggestad, Kristin Roseth Aass, Gunhild Garmo Hov, Hanne Hella, Anne-Marit Sponaas, Therese Standal
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-54193-8

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