Inhibition of Voltage-Gated Na<sup>+</sup> Currents Exerted by KB-R7943 (2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea), an Inhibitor of Na<sup>+</sup>-Ca<sup>2+</sup> Exchanging Process

Inhibition of Voltage-Gated Na<sup>+</sup> Currents Exerted by KB-R7943 (2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea), an Inhibitor of Na<sup>+</sup>-Ca<sup>2+</sup> Exchanging Process

KB-R7943, an isothiourea derivative, has been recognized as an inhibitor in the reverse mode of the Na<sup>+</sup>-Ca<sup>2+</sup> exchanging process. This compound was demonstrated to prevent intracellular Na<sup>+</sup>-dependent Ca<sup>2+</sup> upta...

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Bibliographic Details
Main Authors:	Sheng-Nan Wu, Meng-Cheng Yu
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	International Journal of Molecular Sciences
Subjects:	KB-R7943 Na<sup>+</sup>-Ca<sup>2+</sup> exchange voltage-gated Na<sup>+</sup> current transient Na<sup>+</sup> current late Na<sup>+</sup> current window Na<sup>+</sup> current
Online Access:	https://www.mdpi.com/1422-0067/24/2/1805

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