Gout: objective, indications and adherence to uratelowering therapy

Gout is a chronic systemic inflammatory tophus disease with recurrent arthritis of the peripheral joints in patients with hyperuricemia and the deposition of monosodium urate crystals in various tissues. Only 50% or less of patients receive therapy lowering serum uric acid levels to the target level...

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Main Authors: V. V. Tsurko, T. Ye. Morozova, M. A. Gromova, K. M. Krykhivskaya
Format: Article
Language:Russian
Published: Remedium Group LLC 2019-03-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/2901
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author V. V. Tsurko
T. Ye. Morozova
M. A. Gromova
K. M. Krykhivskaya
author_facet V. V. Tsurko
T. Ye. Morozova
M. A. Gromova
K. M. Krykhivskaya
author_sort V. V. Tsurko
collection DOAJ
description Gout is a chronic systemic inflammatory tophus disease with recurrent arthritis of the peripheral joints in patients with hyperuricemia and the deposition of monosodium urate crystals in various tissues. Only 50% or less of patients receive therapy lowering serum uric acid levels to the target level. The lowering therapy is started with a low dose and subsequent titration in all patients with high UA serum levels in the presence of renal pathology, and in such comorbid diseases as hypertension, heart failure, coronary artery disease.
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spelling doaj.art-718b5f6d797349e3b9c973ced99be9b82023-04-23T06:56:59ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-03-0101727510.21518/2079-701X-2019-1-72-752825Gout: objective, indications and adherence to uratelowering therapyV. V. Tsurko0T. Ye. Morozova1M. A. Gromova2K. M. Krykhivskaya3Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University); Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia,Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia,Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)Gout is a chronic systemic inflammatory tophus disease with recurrent arthritis of the peripheral joints in patients with hyperuricemia and the deposition of monosodium urate crystals in various tissues. Only 50% or less of patients receive therapy lowering serum uric acid levels to the target level. The lowering therapy is started with a low dose and subsequent titration in all patients with high UA serum levels in the presence of renal pathology, and in such comorbid diseases as hypertension, heart failure, coronary artery disease.https://www.med-sovet.pro/jour/article/view/2901gouthyperuricemiamonosodium urate crystalsallopurinolfebuxostat
spellingShingle V. V. Tsurko
T. Ye. Morozova
M. A. Gromova
K. M. Krykhivskaya
Gout: objective, indications and adherence to uratelowering therapy
Медицинский совет
gout
hyperuricemia
monosodium urate crystals
allopurinol
febuxostat
title Gout: objective, indications and adherence to uratelowering therapy
title_full Gout: objective, indications and adherence to uratelowering therapy
title_fullStr Gout: objective, indications and adherence to uratelowering therapy
title_full_unstemmed Gout: objective, indications and adherence to uratelowering therapy
title_short Gout: objective, indications and adherence to uratelowering therapy
title_sort gout objective indications and adherence to uratelowering therapy
topic gout
hyperuricemia
monosodium urate crystals
allopurinol
febuxostat
url https://www.med-sovet.pro/jour/article/view/2901
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AT tyemorozova goutobjectiveindicationsandadherencetourateloweringtherapy
AT magromova goutobjectiveindicationsandadherencetourateloweringtherapy
AT kmkrykhivskaya goutobjectiveindicationsandadherencetourateloweringtherapy