Gout: objective, indications and adherence to uratelowering therapy
Gout is a chronic systemic inflammatory tophus disease with recurrent arthritis of the peripheral joints in patients with hyperuricemia and the deposition of monosodium urate crystals in various tissues. Only 50% or less of patients receive therapy lowering serum uric acid levels to the target level...
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Format: | Article |
Language: | Russian |
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Remedium Group LLC
2019-03-01
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Series: | Медицинский совет |
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Online Access: | https://www.med-sovet.pro/jour/article/view/2901 |
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author | V. V. Tsurko T. Ye. Morozova M. A. Gromova K. M. Krykhivskaya |
author_facet | V. V. Tsurko T. Ye. Morozova M. A. Gromova K. M. Krykhivskaya |
author_sort | V. V. Tsurko |
collection | DOAJ |
description | Gout is a chronic systemic inflammatory tophus disease with recurrent arthritis of the peripheral joints in patients with hyperuricemia and the deposition of monosodium urate crystals in various tissues. Only 50% or less of patients receive therapy lowering serum uric acid levels to the target level. The lowering therapy is started with a low dose and subsequent titration in all patients with high UA serum levels in the presence of renal pathology, and in such comorbid diseases as hypertension, heart failure, coronary artery disease. |
first_indexed | 2024-04-09T16:34:29Z |
format | Article |
id | doaj.art-718b5f6d797349e3b9c973ced99be9b8 |
institution | Directory Open Access Journal |
issn | 2079-701X 2658-5790 |
language | Russian |
last_indexed | 2024-04-09T16:34:29Z |
publishDate | 2019-03-01 |
publisher | Remedium Group LLC |
record_format | Article |
series | Медицинский совет |
spelling | doaj.art-718b5f6d797349e3b9c973ced99be9b82023-04-23T06:56:59ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-03-0101727510.21518/2079-701X-2019-1-72-752825Gout: objective, indications and adherence to uratelowering therapyV. V. Tsurko0T. Ye. Morozova1M. A. Gromova2K. M. Krykhivskaya3Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University); Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia,Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia,Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)Gout is a chronic systemic inflammatory tophus disease with recurrent arthritis of the peripheral joints in patients with hyperuricemia and the deposition of monosodium urate crystals in various tissues. Only 50% or less of patients receive therapy lowering serum uric acid levels to the target level. The lowering therapy is started with a low dose and subsequent titration in all patients with high UA serum levels in the presence of renal pathology, and in such comorbid diseases as hypertension, heart failure, coronary artery disease.https://www.med-sovet.pro/jour/article/view/2901gouthyperuricemiamonosodium urate crystalsallopurinolfebuxostat |
spellingShingle | V. V. Tsurko T. Ye. Morozova M. A. Gromova K. M. Krykhivskaya Gout: objective, indications and adherence to uratelowering therapy Медицинский совет gout hyperuricemia monosodium urate crystals allopurinol febuxostat |
title | Gout: objective, indications and adherence to uratelowering therapy |
title_full | Gout: objective, indications and adherence to uratelowering therapy |
title_fullStr | Gout: objective, indications and adherence to uratelowering therapy |
title_full_unstemmed | Gout: objective, indications and adherence to uratelowering therapy |
title_short | Gout: objective, indications and adherence to uratelowering therapy |
title_sort | gout objective indications and adherence to uratelowering therapy |
topic | gout hyperuricemia monosodium urate crystals allopurinol febuxostat |
url | https://www.med-sovet.pro/jour/article/view/2901 |
work_keys_str_mv | AT vvtsurko goutobjectiveindicationsandadherencetourateloweringtherapy AT tyemorozova goutobjectiveindicationsandadherencetourateloweringtherapy AT magromova goutobjectiveindicationsandadherencetourateloweringtherapy AT kmkrykhivskaya goutobjectiveindicationsandadherencetourateloweringtherapy |