Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides
It has been demonstrated that high lipid content is accompanied with better course and surviving in chronic heart failure (CHF), which was called “the lipids paradox”. There are a very limited number of investigations which studied the relationship of lipid levels and indices of myocardial remodelin...
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| Format: | Article |
| Language: | English |
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Zaporozhye State Medical University
2016-12-01
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| Series: | Zaporožskij Medicinskij Žurnal |
| Subjects: | |
| Online Access: | http://zmj.zsmu.edu.ua/article/view/85496/83148, |
| _version_ | 1818682616324292608 |
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| author | P. P. Bidzilya |
| author_facet | P. P. Bidzilya |
| author_sort | P. P. Bidzilya |
| collection | DOAJ |
| description | It has been demonstrated that high lipid content is accompanied with better course and surviving in chronic heart failure (CHF), which was called “the lipids paradox”. There are a very limited number of investigations which studied the relationship of lipid levels and indices of myocardial remodeling.
Aim. To study the features of myocardial remodeling in patients with CHF with overweight and obesity depending on the total cholesterol (TCL) and triglyceride (TG) levels.
Materials and methods. 230 patients were examined and analyzed 101 case histories of patients of with CHF of I–III functional class on the background of overweight and obesity I–III degree. CHF FC was determined by the classification of the New York Heart Association (NYHA). Normal, excess body weight and degree of abdominal obesity were detected by calculating the body mass index. Biochemical method was used to determine the blood levels of TCL and TG. The condition of myocardial remodeling was investigated by echocardiography.
Results. It has been established, that smallest manifestation of myocardial remodeling was observed in patients with CHF on the background of overweight and obesity with high TCL level. The most severe manifestations of the heart chambers dilatation, left ventricle hypertrophy (LVH), and valvular functional changes characterized the patients with a low TCL concentration. High content of TG was also accompanied by a less pronounced cardiac remodeling, and the normal value of TG was characterized by more profound structural changes of theLV and valvular regurgitation.
Conclusion. At CHF with overweight and obesity, lower TCL and TG levels are accompanied by more severe dilatation of the heart chambers and LVH, the prevalence of LVH eccentric type frequency, deeper functional valve disorders. |
| first_indexed | 2024-12-17T10:21:40Z |
| format | Article |
| id | doaj.art-719054f6d2014764876db60fbc1b69d5 |
| institution | Directory Open Access Journal |
| issn | 2306-4145 2310-1210 |
| language | English |
| last_indexed | 2024-12-17T10:21:40Z |
| publishDate | 2016-12-01 |
| publisher | Zaporozhye State Medical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj.art-719054f6d2014764876db60fbc1b69d52022-12-21T21:52:46ZengZaporozhye State Medical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102016-12-0163438http://dx.doi.org/10.14739/2310-1210.2016.6.85496Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglyceridesP. P. BidzilyaIt has been demonstrated that high lipid content is accompanied with better course and surviving in chronic heart failure (CHF), which was called “the lipids paradox”. There are a very limited number of investigations which studied the relationship of lipid levels and indices of myocardial remodeling. Aim. To study the features of myocardial remodeling in patients with CHF with overweight and obesity depending on the total cholesterol (TCL) and triglyceride (TG) levels. Materials and methods. 230 patients were examined and analyzed 101 case histories of patients of with CHF of I–III functional class on the background of overweight and obesity I–III degree. CHF FC was determined by the classification of the New York Heart Association (NYHA). Normal, excess body weight and degree of abdominal obesity were detected by calculating the body mass index. Biochemical method was used to determine the blood levels of TCL and TG. The condition of myocardial remodeling was investigated by echocardiography. Results. It has been established, that smallest manifestation of myocardial remodeling was observed in patients with CHF on the background of overweight and obesity with high TCL level. The most severe manifestations of the heart chambers dilatation, left ventricle hypertrophy (LVH), and valvular functional changes characterized the patients with a low TCL concentration. High content of TG was also accompanied by a less pronounced cardiac remodeling, and the normal value of TG was characterized by more profound structural changes of theLV and valvular regurgitation. Conclusion. At CHF with overweight and obesity, lower TCL and TG levels are accompanied by more severe dilatation of the heart chambers and LVH, the prevalence of LVH eccentric type frequency, deeper functional valve disorders.http://zmj.zsmu.edu.ua/article/view/85496/83148,Heart FailureCardiac RemodelingLipidsOverweightObesity |
| spellingShingle | P. P. Bidzilya Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides Zaporožskij Medicinskij Žurnal Heart Failure Cardiac Remodeling Lipids Overweight Obesity |
| title | Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides |
| title_full | Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides |
| title_fullStr | Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides |
| title_full_unstemmed | Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides |
| title_short | Myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides |
| title_sort | myocardial remodeling in chronic heart failure with overweight and obesity taking into account the levels of total cholesterol and triglycerides |
| topic | Heart Failure Cardiac Remodeling Lipids Overweight Obesity |
| url | http://zmj.zsmu.edu.ua/article/view/85496/83148, |
| work_keys_str_mv | AT ppbidzilya myocardialremodelinginchronicheartfailurewithoverweightandobesitytakingintoaccountthelevelsoftotalcholesterolandtriglycerides |