Evolutionary divergence and functions of the <it>ADAM </it>and <it>ADAMTS </it>gene families

Evolutionary divergence and functions of the <it>ADAM </it>and <it>ADAMTS </it>gene families

<p>Abstract</p> <p>The 'A-disintegrin and metalloproteinase' (<it>ADAM</it>) and 'A-disintegrin and metalloproteinase with thrombospondin motifs' (<it>ADAMTS</it>) genes make up two similar, yet distinct, gene families. The human and mous...

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Bibliographic Details
Main Authors: Brocker Chad N, Vasiliou Vasilis, Nebert Daniel W
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Human Genomics
Subjects:
ADAM
ADAMTS
<it>gene family integrins</it>
<it>metalloproteinases</it>
<it>peptidase activity</it>
<it>procollagen</it>
<it>proteoglycans</it>
<it>epidermal growth factor domain</it>
<it>thrombospondins domain</it>
<it>potential drug targets</it>
<it>human genome</it>
Online Access:http://www.humgenomics.com/content/4/1/43

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