Design, Synthesis and Preliminary Pharmacological Evaluation of Mutual Prodrug of Non-Steroidal Anti-Inflammatory Drugs Coupling With Natural Anti-Oxidants Via Glycine

Design, Synthesis and Preliminary Pharmacological Evaluation of Mutual Prodrug of Non-Steroidal Anti-Inflammatory Drugs Coupling With Natural Anti-Oxidants Via Glycine

Non-steroidal anti-inflammatory drugs (NSAIDs); naproxen and indomethacin have been conjugated with different antioxidants (thymol, menthol & guaiacol) having antiulcerogenic activity via glycine amino acid as spacer with the objective of obtaining NSAIDs-glycine- antioxidant prodrugs as gastro...

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Bibliographic Details
Main Authors:	Monther Faisal Mahdi, Ashour H. Dawood, Ahmed Kareem Hussein
Format:	Article
Language:	English
Published:	College of Pharmacy / Mustansiriyah University 2013-06-01
Series:	Al-Mustansiriyah Journal of Pharmaceutical Sciences
Subjects:	NSAIDs naproxen; indomethacin; glycine; anti-oxidant; mutual prodrug; antiinflammatory; paw edema
Online Access:	https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/211

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