Fibroinflammatory Signatures Increase with Age in the Human Ovary and Follicular Fluid

Fibroinflammatory Signatures Increase with Age in the Human Ovary and Follicular Fluid

The female reproductive system ages before any other organ system in the body. This phenomenon can have tangible clinical implications leading to infertility, miscarriages, birth defects and systemic deterioration due to estrogen loss. “Fibroinflammation” is a hallmark of aging tissues; there is an...

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Bibliographic Details
Main Authors: Jordan H. Machlin, Seth J. Barishansky, John Kelsh, Megan J. Larmore, Brian W. Johnson, Michele T. Pritchard, Mary Ellen Pavone, Francesca E. Duncan
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
cytokine
fibrosis
inflammation
human
ovary
TGFβ3
Online Access:https://www.mdpi.com/1422-0067/22/9/4902

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