Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties
<i>Ferula</i> is a genus of flowering plants known for its edible and medicinal properties. Since ancient times, many species of <i>Ferula</i> have been used in traditional medicine to treat various health issues across countries, such as digestive disorders, respiratory prob...
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| Format: | Article |
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MDPI AG
2023-12-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/13/1/7 |
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| author | Junchi Wang Qi Zheng Huaxiang Wang Leiling Shi Guoping Wang Yaqin Zhao Congzhao Fan Jianyong Si |
| author_facet | Junchi Wang Qi Zheng Huaxiang Wang Leiling Shi Guoping Wang Yaqin Zhao Congzhao Fan Jianyong Si |
| author_sort | Junchi Wang |
| collection | DOAJ |
| description | <i>Ferula</i> is a genus of flowering plants known for its edible and medicinal properties. Since ancient times, many species of <i>Ferula</i> have been used in traditional medicine to treat various health issues across countries, such as digestive disorders, respiratory problems, and even as a remedy for headaches and toothaches. In addition, they are also used as a flavoring agent in various cuisines. As the main active ingredients in <i>Ferula</i>, sesquiterpenes and their derivatives, especially sesquiterpene coumarins, sesquiterpene phenylpropanoids, and sesquiterpene chromones, have attracted the attention of scientists due to the diversity of their chemical structures, as well as their extensive and promising biological properties, such as antioxidative, anti-inflammatory, antibacterial properties. However, there has not been a comprehensive review of sesquiterpenes and their derivatives from this plant. This review aims to provide an overview of the chemical structures, biosynthetic pathways, and biological properties of sesquiterpenes and sesquiterpene derivatives from <i>Ferula</i>, which may help guide future research directions and possible application methods for this valuable edible and medicinal plant. |
| first_indexed | 2024-03-08T11:07:18Z |
| format | Article |
| id | doaj.art-7194bb45d6854697b440be30a165f031 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-08T11:07:18Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-7194bb45d6854697b440be30a165f0312024-01-26T14:39:18ZengMDPI AGAntioxidants2076-39212023-12-01131710.3390/antiox13010007Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological PropertiesJunchi Wang0Qi Zheng1Huaxiang Wang2Leiling Shi3Guoping Wang4Yaqin Zhao5Congzhao Fan6Jianyong Si7The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaThe Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaThe Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaXinjiang Institute of Chinese Materia Medica and Ethnodrug, Urumqi 830002, ChinaXinjiang Institute of Chinese Materia Medica and Ethnodrug, Urumqi 830002, ChinaXinjiang Institute of Chinese Materia Medica and Ethnodrug, Urumqi 830002, ChinaXinjiang Institute of Chinese Materia Medica and Ethnodrug, Urumqi 830002, ChinaThe Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China<i>Ferula</i> is a genus of flowering plants known for its edible and medicinal properties. Since ancient times, many species of <i>Ferula</i> have been used in traditional medicine to treat various health issues across countries, such as digestive disorders, respiratory problems, and even as a remedy for headaches and toothaches. In addition, they are also used as a flavoring agent in various cuisines. As the main active ingredients in <i>Ferula</i>, sesquiterpenes and their derivatives, especially sesquiterpene coumarins, sesquiterpene phenylpropanoids, and sesquiterpene chromones, have attracted the attention of scientists due to the diversity of their chemical structures, as well as their extensive and promising biological properties, such as antioxidative, anti-inflammatory, antibacterial properties. However, there has not been a comprehensive review of sesquiterpenes and their derivatives from this plant. This review aims to provide an overview of the chemical structures, biosynthetic pathways, and biological properties of sesquiterpenes and sesquiterpene derivatives from <i>Ferula</i>, which may help guide future research directions and possible application methods for this valuable edible and medicinal plant.https://www.mdpi.com/2076-3921/13/1/7<i>Ferula</i>sesquiterpenebiosynthetic pathwayantioxidativeantibacterialanti-inflammatory |
| spellingShingle | Junchi Wang Qi Zheng Huaxiang Wang Leiling Shi Guoping Wang Yaqin Zhao Congzhao Fan Jianyong Si Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties Antioxidants <i>Ferula</i> sesquiterpene biosynthetic pathway antioxidative antibacterial anti-inflammatory |
| title | Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties |
| title_full | Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties |
| title_fullStr | Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties |
| title_full_unstemmed | Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties |
| title_short | Sesquiterpenes and Sesquiterpene Derivatives from <i>Ferula</i>: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties |
| title_sort | sesquiterpenes and sesquiterpene derivatives from i ferula i their chemical structures biosynthetic pathways and biological properties |
| topic | <i>Ferula</i> sesquiterpene biosynthetic pathway antioxidative antibacterial anti-inflammatory |
| url | https://www.mdpi.com/2076-3921/13/1/7 |
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