Cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus

Cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus

IntroductionDeterioration of cognitive functions is commonly associated with aging, although there is wide variation in the onset and manifestation. Albeit heterogeneity in age-related cognitive decline has been studied at the cellular and molecular level, there is poor evidence for electrophysiolog...

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Main Authors: Claudia Sagheddu, Tamara Stojanovic, Shima Kouhnavardi, Artem Savchenko, Ahmed M. Hussein, Marco Pistis, Francisco J. Monje, Roberto Plasenzotti, Mohammed Aufy, Christian R. Studenik, Jana Lubec, Gert Lubec
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
dopamine
LTP
learning and memory
in vivo electrophysiology
VTA GABAergic and VTA glutamatergic neurons
dementia
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1357347/full

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