An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components
Alpha Fetoprotein (AFP) producing gastric carcinomas are very rare and have unique clinicopathological features and an extremely poor prognosis. Here, we report a case of AFP producing gastric carcinoma with three distinct histomorphologic patterns such as yolk sac like, hepatoid, tubular and papi...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2017-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/10546/29454_CE[Ra]_F(Sh)_PF1(PG_GG)_PFA(SY_GG).pdf |
| _version_ | 1811279602420547584 |
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| author | Archana Lakshmanan Ann Kurian Annapurneswari Subramanyan Ayyappan Srinivasan |
| author_facet | Archana Lakshmanan Ann Kurian Annapurneswari Subramanyan Ayyappan Srinivasan |
| author_sort | Archana Lakshmanan |
| collection | DOAJ |
| description | Alpha Fetoprotein (AFP) producing gastric carcinomas are very rare and have unique clinicopathological features and an extremely
poor prognosis. Here, we report a case of AFP producing gastric carcinoma with three distinct histomorphologic patterns such as
yolk sac like, hepatoid, tubular and papillary adenocarcinoma components. The uniqueness of this case is absence of metastases
and associated findings such as fundic gland polyposis with varying degrees of dysplasia, gastric and duodenal well differentiated
neuroendocrine tumour and rectal ganglioneuroma. The patient is symptom free as of two and half year’s postoperative period. AFP
producing gastric tumours although rare, need to be identified as it is known to carry poor prognosis. |
| first_indexed | 2024-04-13T00:57:30Z |
| format | Article |
| id | doaj.art-719bc2a5b4314cc5bcbc0f16a02c6047 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-13T00:57:30Z |
| publishDate | 2017-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-719bc2a5b4314cc5bcbc0f16a02c60472022-12-22T03:09:35ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-09-01119ED03ED0510.7860/JCDR/2017/29454.10546An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma ComponentsArchana Lakshmanan0Ann Kurian1Annapurneswari Subramanyan2Ayyappan Srinivasan3Junior Consultant, Department of Histopathology, Apollo Hospitals, Chennai, Tamil Nadu, India.Senior Consultant, Department of Histopathology, Apollo Hospitals, Chennai, Tamil Nadu, India.Senior Consultant, Department of Histopathology, Apollo Hospitals, Chennai, Tamil Nadu, India.Senior Consultant, Department of Surgical Oncology, Apollo Hospitals, Chennai, Tamil Nadu, India.Alpha Fetoprotein (AFP) producing gastric carcinomas are very rare and have unique clinicopathological features and an extremely poor prognosis. Here, we report a case of AFP producing gastric carcinoma with three distinct histomorphologic patterns such as yolk sac like, hepatoid, tubular and papillary adenocarcinoma components. The uniqueness of this case is absence of metastases and associated findings such as fundic gland polyposis with varying degrees of dysplasia, gastric and duodenal well differentiated neuroendocrine tumour and rectal ganglioneuroma. The patient is symptom free as of two and half year’s postoperative period. AFP producing gastric tumours although rare, need to be identified as it is known to carry poor prognosis.https://jcdr.net/articles/PDF/10546/29454_CE[Ra]_F(Sh)_PF1(PG_GG)_PFA(SY_GG).pdfgastric carcinomastomachtumour marker |
| spellingShingle | Archana Lakshmanan Ann Kurian Annapurneswari Subramanyan Ayyappan Srinivasan An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components Journal of Clinical and Diagnostic Research gastric carcinoma stomach tumour marker |
| title | An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components |
| title_full | An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components |
| title_fullStr | An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components |
| title_full_unstemmed | An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components |
| title_short | An Alpha Fetoprotein Producing Gastric Tumor with Yolk Sac, Hepatoid and Papillary Adenocarcinoma Components |
| title_sort | alpha fetoprotein producing gastric tumor with yolk sac hepatoid and papillary adenocarcinoma components |
| topic | gastric carcinoma stomach tumour marker |
| url | https://jcdr.net/articles/PDF/10546/29454_CE[Ra]_F(Sh)_PF1(PG_GG)_PFA(SY_GG).pdf |
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