Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines
Worldwide, rotavirus infection has been a leading cause of severe diarrhea morbidity and mortality. Two rotavirus vaccines have been used in the National Immunization Program (NIP) in Mexico; two-dose Rotarix from 2006 to 2011 and three-dose RotaTeq since 2011. This study assessed coverage (receivin...
| Príomhchruthaitheoirí: | , , , , , , , , |
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| Formáid: | Alt |
| Teanga: | English |
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Taylor & Francis Group
2019-06-01
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| Sraith: | Human Vaccines & Immunotherapeutics |
| Ábhair: | |
| Rochtain ar líne: | http://dx.doi.org/10.1080/21645515.2018.1540827 |
| _version_ | 1827809783070064640 |
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| author | Gerardo Luna-Casas Patricia Juliao Roberto Carreño-Manjarrez Andrés Castañeda-Prado Maria Yolanda Cervantes-Apolinar Ricardo Navarro-Rodriguez Gilberto Sánchez-González Ricardo Cortés-Alcalá Rodrigo DeAntonio |
| author_facet | Gerardo Luna-Casas Patricia Juliao Roberto Carreño-Manjarrez Andrés Castañeda-Prado Maria Yolanda Cervantes-Apolinar Ricardo Navarro-Rodriguez Gilberto Sánchez-González Ricardo Cortés-Alcalá Rodrigo DeAntonio |
| author_sort | Gerardo Luna-Casas |
| collection | DOAJ |
| description | Worldwide, rotavirus infection has been a leading cause of severe diarrhea morbidity and mortality. Two rotavirus vaccines have been used in the National Immunization Program (NIP) in Mexico; two-dose Rotarix from 2006 to 2011 and three-dose RotaTeq since 2011. This study assessed coverage (receiving at least one dose or full dose series) in eligible infants, compliance (% completing dose series and % completing series on schedule) in eligible infants vaccinated with Rotarix (2010) versus RotaTeq (2012), using Mexican Social Security Institute data nationwide and by regions. In 2010, 80.7% received at least one dose of Rotarix, 75.6% received both doses and 57.0% received both doses on schedule. In 2012, 85.7% received at least one dose of RotaTeq, 61.0% received all three doses and 43.2% received all three doses on schedule. More eligible infants received all doses with Rotarix versus RotaTeq (p < 0.001). Among infants vaccinated with Rotarix versus RotaTeq, 93.7% versus 71.1% completed full series (p < 0.001), and 75.5% versus 70.9% completed full series on schedule (p = 0.105), respectively. The full series coverage and compliance decreased in all regions with RotaTeq compared with Rotarix. In conclusion, rotavirus vaccination has successfully reduced morbidity and mortality in children under 5 years in Mexico. This study found significant differences in full series coverage and compliance among infants and a higher proportion of completed scheduled at an earlier age in Mexico when comparing a two-dose vaccine in 2010 with a three-dose vaccine in 2012. Such differences might need to be taken into consideration to maximize NIP benefits, including early protection of the rotavirus vaccination program. |
| first_indexed | 2024-03-11T22:44:53Z |
| format | Article |
| id | doaj.art-719d4ae5c11a48ac8b4f5e4989ac2056 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:44:53Z |
| publishDate | 2019-06-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-719d4ae5c11a48ac8b4f5e4989ac20562023-09-22T08:38:24ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2019-06-011561251125910.1080/21645515.2018.15408271540827Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccinesGerardo Luna-Casas0Patricia Juliao1Roberto Carreño-Manjarrez2Andrés Castañeda-Prado3Maria Yolanda Cervantes-Apolinar4Ricardo Navarro-Rodriguez5Gilberto Sánchez-González6Ricardo Cortés-Alcalá7Rodrigo DeAntonio8Estimatio SCGSK, City of KnowledgeGSK, Calz México-XochimilcoEstimatio SCGSKEstimatio SCEstimatio SCGSKGSK, City of KnowledgeWorldwide, rotavirus infection has been a leading cause of severe diarrhea morbidity and mortality. Two rotavirus vaccines have been used in the National Immunization Program (NIP) in Mexico; two-dose Rotarix from 2006 to 2011 and three-dose RotaTeq since 2011. This study assessed coverage (receiving at least one dose or full dose series) in eligible infants, compliance (% completing dose series and % completing series on schedule) in eligible infants vaccinated with Rotarix (2010) versus RotaTeq (2012), using Mexican Social Security Institute data nationwide and by regions. In 2010, 80.7% received at least one dose of Rotarix, 75.6% received both doses and 57.0% received both doses on schedule. In 2012, 85.7% received at least one dose of RotaTeq, 61.0% received all three doses and 43.2% received all three doses on schedule. More eligible infants received all doses with Rotarix versus RotaTeq (p < 0.001). Among infants vaccinated with Rotarix versus RotaTeq, 93.7% versus 71.1% completed full series (p < 0.001), and 75.5% versus 70.9% completed full series on schedule (p = 0.105), respectively. The full series coverage and compliance decreased in all regions with RotaTeq compared with Rotarix. In conclusion, rotavirus vaccination has successfully reduced morbidity and mortality in children under 5 years in Mexico. This study found significant differences in full series coverage and compliance among infants and a higher proportion of completed scheduled at an earlier age in Mexico when comparing a two-dose vaccine in 2010 with a three-dose vaccine in 2012. Such differences might need to be taken into consideration to maximize NIP benefits, including early protection of the rotavirus vaccination program.http://dx.doi.org/10.1080/21645515.2018.1540827rotarixrotateqrotavirusmexicodosingcoveragecompliance |
| spellingShingle | Gerardo Luna-Casas Patricia Juliao Roberto Carreño-Manjarrez Andrés Castañeda-Prado Maria Yolanda Cervantes-Apolinar Ricardo Navarro-Rodriguez Gilberto Sánchez-González Ricardo Cortés-Alcalá Rodrigo DeAntonio Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines Human Vaccines & Immunotherapeutics rotarix rotateq rotavirus mexico dosing coverage compliance |
| title | Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines |
| title_full | Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines |
| title_fullStr | Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines |
| title_full_unstemmed | Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines |
| title_short | Vaccine coverage and compliance in Mexico with the two-dose and three-dose rotavirus vaccines |
| title_sort | vaccine coverage and compliance in mexico with the two dose and three dose rotavirus vaccines |
| topic | rotarix rotateq rotavirus mexico dosing coverage compliance |
| url | http://dx.doi.org/10.1080/21645515.2018.1540827 |
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