SEE: a novel multi-objective evolutionary algorithm for identifying SNP epistasis in genome-wide association studies

SEE: a novel multi-objective evolutionary algorithm for identifying SNP epistasis in genome-wide association studies

Although genome-wide association studies play an increasingly important role in identifying causes of complex diseases, detecting SNP epistasis in these studies is a computational challenge. The existing methods are usually based on a single-correlation model between SNP combinations and phenotype a...

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Bibliographic Details
Main Authors: Liyan Sun, Guixia Liu, Lingtao Su, Rongquan Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
single-nucleotide polymorphism
epistasis
genome-wide association studies
evolutionary algorithm
Online Access:http://dx.doi.org/10.1080/13102818.2019.1593052

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