Pathophysiology of Increased Fetal Nuchal Translucency Thickness

Increased fetal nuchal translucency thickness is associated with trisomy 13, trisomy 18, trisomy 21, Turner syndrome, other sex chromosome abnormalities, as well as many fetal anomalies and genetic syndromes. This article provides a comprehensive review of the cardinal proposed pathophysiology inclu...

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Main Author: Chih-Ping Chen
Format: Article
Language:English
Published: Elsevier 2010-06-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455910600290
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author Chih-Ping Chen
author_facet Chih-Ping Chen
author_sort Chih-Ping Chen
collection DOAJ
description Increased fetal nuchal translucency thickness is associated with trisomy 13, trisomy 18, trisomy 21, Turner syndrome, other sex chromosome abnormalities, as well as many fetal anomalies and genetic syndromes. This article provides a comprehensive review of the cardinal proposed pathophysiology including altered composition of the extracellular matrix, abnormalities of the heart and great arteries, and disturbed or delayed lymphatic development.
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spelling doaj.art-719e4ac7492e4f8fa28bdad99c1368fd2022-12-22T03:01:16ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592010-06-0149213313810.1016/S1028-4559(10)60029-0Pathophysiology of Increased Fetal Nuchal Translucency ThicknessChih-Ping Chen0Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, TaiwanIncreased fetal nuchal translucency thickness is associated with trisomy 13, trisomy 18, trisomy 21, Turner syndrome, other sex chromosome abnormalities, as well as many fetal anomalies and genetic syndromes. This article provides a comprehensive review of the cardinal proposed pathophysiology including altered composition of the extracellular matrix, abnormalities of the heart and great arteries, and disturbed or delayed lymphatic development.http://www.sciencedirect.com/science/article/pii/S1028455910600290fetusnuchal translucencypathophysiology
spellingShingle Chih-Ping Chen
Pathophysiology of Increased Fetal Nuchal Translucency Thickness
Taiwanese Journal of Obstetrics & Gynecology
fetus
nuchal translucency
pathophysiology
title Pathophysiology of Increased Fetal Nuchal Translucency Thickness
title_full Pathophysiology of Increased Fetal Nuchal Translucency Thickness
title_fullStr Pathophysiology of Increased Fetal Nuchal Translucency Thickness
title_full_unstemmed Pathophysiology of Increased Fetal Nuchal Translucency Thickness
title_short Pathophysiology of Increased Fetal Nuchal Translucency Thickness
title_sort pathophysiology of increased fetal nuchal translucency thickness
topic fetus
nuchal translucency
pathophysiology
url http://www.sciencedirect.com/science/article/pii/S1028455910600290
work_keys_str_mv AT chihpingchen pathophysiologyofincreasedfetalnuchaltranslucencythickness