Mortality and prognostic factors for spontaneous pneumothorax in older adults.
Spontaneous pneumothorax occurs predominantly in young males and older adults, often as a secondary condition, and can be refractory and fatal. This study aimed to investigate the mortality and prognostic factors for pneumothorax in older patients. We retrospectively cohort studied patients with pne...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0291233 |
| _version_ | 1797682737874731008 |
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| author | Saori Nishizawa Kazunori Tobino Yousuke Murakami Kazuki Uchida Takafumi Kawabata Hiroyuki Ota Yuri Hiramatsu Takuto Sueyasu Kosuke Tsuruno |
| author_facet | Saori Nishizawa Kazunori Tobino Yousuke Murakami Kazuki Uchida Takafumi Kawabata Hiroyuki Ota Yuri Hiramatsu Takuto Sueyasu Kosuke Tsuruno |
| author_sort | Saori Nishizawa |
| collection | DOAJ |
| description | Spontaneous pneumothorax occurs predominantly in young males and older adults, often as a secondary condition, and can be refractory and fatal. This study aimed to investigate the mortality and prognostic factors for pneumothorax in older patients. We retrospectively cohort studied patients with pneumothorax aged ≥65 years who visited our department from October 2012 to January 2019. Data on sex, age, medical history, smoking history, underlying lung disease, treatment, and prognosis were extracted from medical records. Cox proportional hazards regression analysis was used to investigate pneumothorax mortality and prognostic factors. In total, 239 patients were included. Among them, 36 (15%) died during hospitalization. Respiratory disease was the direct cause of death in 30 patients (83.3%), and 211 (88.3%) patients had underlying lung disease. The incidence of pneumonia in our hospital was 22.6% (54 cases). On admission, the mortality rate was 33% (18/54) in patients with concomitant pneumonia; univariate analysis showed significant differences in the Charlson Comorbidity Index (CCI), activities of daily living (ADL), and concomitant pneumonia. In the Cox proportional hazards analysis of ADL (p = 0.09), CCI (p = 0.05), and concomitant pneumonia on admission (p = 0.02), concomitant pneumonia on admission was found to be an independent predictor of in-hospital mortality. This study suggests that concomitant pneumonia at admission may be a mortality risk factor for pneumothorax. |
| first_indexed | 2024-03-12T00:04:11Z |
| format | Article |
| id | doaj.art-719fc530d082433fab49a3a5299ab5c8 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-12T00:04:11Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-719fc530d082433fab49a3a5299ab5c82023-09-17T05:31:15ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01189e029123310.1371/journal.pone.0291233Mortality and prognostic factors for spontaneous pneumothorax in older adults.Saori NishizawaKazunori TobinoYousuke MurakamiKazuki UchidaTakafumi KawabataHiroyuki OtaYuri HiramatsuTakuto SueyasuKosuke TsurunoSpontaneous pneumothorax occurs predominantly in young males and older adults, often as a secondary condition, and can be refractory and fatal. This study aimed to investigate the mortality and prognostic factors for pneumothorax in older patients. We retrospectively cohort studied patients with pneumothorax aged ≥65 years who visited our department from October 2012 to January 2019. Data on sex, age, medical history, smoking history, underlying lung disease, treatment, and prognosis were extracted from medical records. Cox proportional hazards regression analysis was used to investigate pneumothorax mortality and prognostic factors. In total, 239 patients were included. Among them, 36 (15%) died during hospitalization. Respiratory disease was the direct cause of death in 30 patients (83.3%), and 211 (88.3%) patients had underlying lung disease. The incidence of pneumonia in our hospital was 22.6% (54 cases). On admission, the mortality rate was 33% (18/54) in patients with concomitant pneumonia; univariate analysis showed significant differences in the Charlson Comorbidity Index (CCI), activities of daily living (ADL), and concomitant pneumonia. In the Cox proportional hazards analysis of ADL (p = 0.09), CCI (p = 0.05), and concomitant pneumonia on admission (p = 0.02), concomitant pneumonia on admission was found to be an independent predictor of in-hospital mortality. This study suggests that concomitant pneumonia at admission may be a mortality risk factor for pneumothorax.https://doi.org/10.1371/journal.pone.0291233 |
| spellingShingle | Saori Nishizawa Kazunori Tobino Yousuke Murakami Kazuki Uchida Takafumi Kawabata Hiroyuki Ota Yuri Hiramatsu Takuto Sueyasu Kosuke Tsuruno Mortality and prognostic factors for spontaneous pneumothorax in older adults. PLoS ONE |
| title | Mortality and prognostic factors for spontaneous pneumothorax in older adults. |
| title_full | Mortality and prognostic factors for spontaneous pneumothorax in older adults. |
| title_fullStr | Mortality and prognostic factors for spontaneous pneumothorax in older adults. |
| title_full_unstemmed | Mortality and prognostic factors for spontaneous pneumothorax in older adults. |
| title_short | Mortality and prognostic factors for spontaneous pneumothorax in older adults. |
| title_sort | mortality and prognostic factors for spontaneous pneumothorax in older adults |
| url | https://doi.org/10.1371/journal.pone.0291233 |
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