Mask R-CNN provides efficient and accurate measurement of chondrocyte viability in the label-free assessment of articular cartilage

Mask R-CNN provides efficient and accurate measurement of chondrocyte viability in the label-free assessment of articular cartilage

Objective: Chondrocyte viability (CV) can be measured with the label-free method using second harmonic generation (SHG) and two-photon excitation autofluorescence (TPAF) imaging. To automate the image processing for the label-free CV measurement, we previously demonstrated a two-step deep-learning m...

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Bibliographic Details
Main Authors: Hongming Fan, Pei Xu, Xun Chen, Yang Li, Zhao Zhang, Jennifer Hsu, Michael Le, Emily Ye, Bruce Gao, Harry Demos, Hai Yao, Tong Ye
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Nonlinear optical microscopy
Autofluorescence
Second harmonic generation
Deep learning segmentation
Chondrocyte viability
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913123000821

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