The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration

The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration

Abstract Neurodegenerative diseases encompass a heterogeneous group of conditions characterised by the progressive degeneration of the structure and function of the central or peripheral nervous systems. The pathogenic mechanisms underlying these diseases are not fully understood. However, a central...

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Bibliographic Details
Main Authors: Katherine Fodder, Rohan de Silva, Thomas T. Warner, Conceição Bettencourt
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Acta Neuropathologica Communications
Subjects:
DNA methylation
Oligodendrocytes
Neurodegeneration
Myelin
Epigenetics
Human brain
Online Access:https://doi.org/10.1186/s40478-023-01607-9

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