Treating Cocaine Addiction, Obesity, and Emotional Disorders by Viral Gene Transfer of Butyrylcholinesterase

Treating Cocaine Addiction, Obesity, and Emotional Disorders by Viral Gene Transfer of Butyrylcholinesterase

Butyrylcholinesterase (BChE), a plasma enzyme that hydrolyses the neurotransmitter, acetylcholine relatively well, with far lower efficiency than acetylcholinesterase (AChE) but with the capability to degrade a broad range of bioactive esters. AChE is universally understood as essential to cholinerg...

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Bibliographic Details
Main Authors: Stephen Brimijoin, Yang Gao, Liyi Geng, Vicky P. Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
butyrylcholinesterase
cocaine
ghrelin
addiction
obesity
stress
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00112/full

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