Serrated polyposis syndrome associated with long-standing inflammatory bowel disease
Inflammatory bowel disease (IBD) patients are at an increased risk of developing colorectal cancer (CRC), which is thought to develop via the adenoma-carcinoma pathway. Since the discovery of the serrated carcinogenesis pathway and serrated polyposis syndrome (SPS), the incidence of carcinomas arisi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Aran Ediciones
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| Series: | Revista Espanola de Enfermedades Digestivas |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082017001100011&lng=en&tlng=en |
| _version_ | 1818267976190656512 |
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| author | Jesús Castro Miriam Cuatrecasas Francesc Balaguer Elena Ricart María Pellisé |
| author_facet | Jesús Castro Miriam Cuatrecasas Francesc Balaguer Elena Ricart María Pellisé |
| author_sort | Jesús Castro |
| collection | DOAJ |
| description | Inflammatory bowel disease (IBD) patients are at an increased risk of developing colorectal cancer (CRC), which is thought to develop via the adenoma-carcinoma pathway. Since the discovery of the serrated carcinogenesis pathway and serrated polyposis syndrome (SPS), the incidence of carcinomas arising from serrated lesions in IBD patients has increased. We report three cases of long-standing IBD patients with associated serrated polyposis syndrome. At present, the pathophysiology of serrated lesions in IBD patients is not fully understood and there is a lack of strong evidence to confirm whether the manifestation of both conditions represents an increased risk of developing cancer. Therefore, more accurate surveillance guidelines are needed and are being actively investigated at present. |
| first_indexed | 2024-12-12T20:31:09Z |
| format | Article |
| id | doaj.art-71ab0b0f6dda46a08d27659444472d4c |
| institution | Directory Open Access Journal |
| issn | 1130-0108 |
| language | English |
| last_indexed | 2024-12-12T20:31:09Z |
| publisher | Aran Ediciones |
| record_format | Article |
| series | Revista Espanola de Enfermedades Digestivas |
| spelling | doaj.art-71ab0b0f6dda46a08d27659444472d4c2022-12-22T00:13:01ZengAran EdicionesRevista Espanola de Enfermedades Digestivas1130-01081091179679810.17235/reed.2017.5068/2017S1130-01082017001100011Serrated polyposis syndrome associated with long-standing inflammatory bowel diseaseJesús Castro0Miriam Cuatrecasas1Francesc Balaguer2Elena Ricart3María Pellisé4Hospital Clinic BarcelonaUniversidad de BarcelonaHospital Clinic BarcelonaHospital Clinic BarcelonaHospital Clinic BarcelonaInflammatory bowel disease (IBD) patients are at an increased risk of developing colorectal cancer (CRC), which is thought to develop via the adenoma-carcinoma pathway. Since the discovery of the serrated carcinogenesis pathway and serrated polyposis syndrome (SPS), the incidence of carcinomas arising from serrated lesions in IBD patients has increased. We report three cases of long-standing IBD patients with associated serrated polyposis syndrome. At present, the pathophysiology of serrated lesions in IBD patients is not fully understood and there is a lack of strong evidence to confirm whether the manifestation of both conditions represents an increased risk of developing cancer. Therefore, more accurate surveillance guidelines are needed and are being actively investigated at present.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082017001100011&lng=en&tlng=enSerrated polyposis syndromeUlcerative colitisCrohn's diseaseInflammatory bowel diseaseColonoscopyColorectal cancerChromoendoscopy |
| spellingShingle | Jesús Castro Miriam Cuatrecasas Francesc Balaguer Elena Ricart María Pellisé Serrated polyposis syndrome associated with long-standing inflammatory bowel disease Revista Espanola de Enfermedades Digestivas Serrated polyposis syndrome Ulcerative colitis Crohn's disease Inflammatory bowel disease Colonoscopy Colorectal cancer Chromoendoscopy |
| title | Serrated polyposis syndrome associated with long-standing inflammatory bowel disease |
| title_full | Serrated polyposis syndrome associated with long-standing inflammatory bowel disease |
| title_fullStr | Serrated polyposis syndrome associated with long-standing inflammatory bowel disease |
| title_full_unstemmed | Serrated polyposis syndrome associated with long-standing inflammatory bowel disease |
| title_short | Serrated polyposis syndrome associated with long-standing inflammatory bowel disease |
| title_sort | serrated polyposis syndrome associated with long standing inflammatory bowel disease |
| topic | Serrated polyposis syndrome Ulcerative colitis Crohn's disease Inflammatory bowel disease Colonoscopy Colorectal cancer Chromoendoscopy |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082017001100011&lng=en&tlng=en |
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