Aldo keto reductases 1B in endocrinology and metabolism

Aldo keto reductases 1B in endocrinology and metabolism

The aldose reductase (human AKR1B1/mouse Akr1b3) has been the focus of many research because of its role in diabetic complications. The starting point of these alterations is the massive entry of glucose in polyol pathway where it is converted into sorbitol by this enzyme. However, the issue of aldo...

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Bibliographic Details
Main Authors: Emilie ePastel, Jean-Christophe ePointud, Fanny eVolat, Antoine eMartinez, Anne-Marie eLefrançois-Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Pharmacology
Subjects:
Adipose Tissue
Metabolism
Prostaglandins
Aldose reductases
Enterohepatic tissue
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00148/full

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