Suppression of Interferon-α Treatment Response by Host Negative Factors in Hepatitis B Virus Infection

Suppression of Interferon-α Treatment Response by Host Negative Factors in Hepatitis B Virus Infection

Chronic hepatitis B virus (CHB) infection remains a major global public health issue for which there is still lacking effective curative treatment. Interferon-α (IFN-α) and its pegylated form have been approved as an anti-HBV drug with the advantage of antiviral activity and host immunity against HB...

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Bibliographic Details
Main Authors: Jiayi Wang, Lingyao Du, Hong Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Medicine
Subjects:
chronic hepatitis B
interferon-α
negative regulators
host factors
non-response
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.784172/full

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