Validating core therapeutic targets for osteoporosis treatment based on integrating network pharmacology and informatics
Objective: Our goal was to find metabolism-related lncRNAs that were associated with osteoporosis (OP) and construct a model for predicting OP progression using these lncRNAs. Methods: The GEO database was employed to obtain gene expression profiles. The WGCNA technique and differential expression a...
Main Authors: | Shiyang Weng, Huichao Fu, Shengxiang Xu, Jieruo Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
|
Series: | SLAS Technology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2472630324000049 |
Similar Items
-
Identified lncRNAs functional modules and genes in prediabetes with hypertriglyceridemia by weighted gene co-expression network analysis
by: Mengzi Sun, et al.
Published: (2022-05-01) -
Identification of Key LncRNAs and Pathways in Prediabetes and Type 2 Diabetes Mellitus for Hypertriglyceridemia Patients Based on Weighted Gene Co-Expression Network Analysis
by: Shoumeng Yan, et al.
Published: (2022-01-01) -
The role of lncRNAs and exosomal lncRNAs in cancer metastasis
by: Yutong Zhang, et al.
Published: (2023-09-01) -
Role of LncRNAs and CircRNAs in Bone Metabolism and Osteoporosis
by: Suryaji Patil, et al.
Published: (2020-11-01) -
Insights into the defensive roles of lncRNAs during Mycoplasma pneumoniae infection
by: Zhujun Yang, et al.
Published: (2024-03-01)