Allogeneic Hematopoietic Stem Cell Transplantation for Children With Acute Lymphoblastic Leukemia: Shifting Indications in the Era of Immunotherapy

Allogeneic Hematopoietic Stem Cell Transplantation for Children With Acute Lymphoblastic Leukemia: Shifting Indications in the Era of Immunotherapy

Pediatric acute lymphoblastic leukemia generally carries a good prognosis, and most children will be cured and become long-term survivors. However, a portion of children will harbor high-risk features at the time of diagnosis, have a poor response to upfront therapy, or suffer relapse necessitating...

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Bibliographic Details
Main Authors: Tony H. Truong, Cristian Jinca, Georg Mann, Smaranda Arghirescu, Jochen Buechner, Pietro Merli, James A. Whitlock
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pediatrics
Subjects:
hematopoietic stem cell transplant (HSCT)
acute lympoblastic leukemia
indications and outcome
immunotherapy
children
pediatrics
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.782785/full

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