The effect of spermidine on autoimmunity and beta cell function in NOD mice

The effect of spermidine on autoimmunity and beta cell function in NOD mice

Abstract Spermidine is a natural polyamine which was shown to prolong lifespan of organisms and to improve cardiac and cognitive function. Spermidine was also reported to reduce inflammation and modulate T-cells. Autophagy is one of the mechanisms that spermidine exerts its effect. Autophagy is vita...

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Bibliographic Details
Main Authors: Ceren Karacay, Barbara Prietl, Clemens Harer, Barbara Ehall, Christoph W. Haudum, Kaddour Bounab, Joakim Franz, Tobias Eisenberg, Frank Madeo, Dagmar Kolb, Kerstin Hingerl, Markus Hausl, Christoph Magnes, Selma I. Mautner, Petra Kotzbeck, Thomas R. Pieber
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08168-2

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