Chronic-phase chronic myeloid leukemia: Incidence of BCR/ABL transcript and its correlation with presenting features, response to treatment, and survival

Chronic-phase chronic myeloid leukemia: Incidence of BCR/ABL transcript and its correlation with presenting features, response to treatment, and survival

Introduction: Chronic myeloid leukemia (CML) is characterized by Philadelphia chromosome resulting in the fusion between the BCR gene, located on chromosome 22, and the ABL gene on chromosome 9. The prognostic significance of BCR-ABL transcript variants in CML is controversial. The aim of the curren...

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Bibliographic Details
Main Authors: Baraa Laabidi, Nader Slama, Ines Ouahchi, Wiem Boufrikha, Mohamed Adnene Laatiri
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Leukemia Research Reports
Subjects:
Myeloproliferative disorder
Chronic phase
Philadelphia chromosome
BCR-ABL transcript
Imatinib mesylate
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048923000134

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