Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees.

Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees.

To date, the Centre d'Etude Polymorphism Humain (CEPH) cell line model has only been used as a pharmacogenomic tool to evaluate which genes are responsible for the disparity in response to a single drug. The purpose of this study was demonstrate the model's ability to establish a specific...

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Bibliographic Details
Main Authors: Venita Gresham Watson, Alison Motsinger-Reif, Nicholas E Hardison, Eric J Peters, Tammy M Havener, Lorraine Everitt, James Todd Auman, Daniel L Comins, Howard L McLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3088663?pdf=render

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http://europepmc.org/articles/PMC3088663?pdf=render

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