Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees.
To date, the Centre d'Etude Polymorphism Humain (CEPH) cell line model has only been used as a pharmacogenomic tool to evaluate which genes are responsible for the disparity in response to a single drug. The purpose of this study was demonstrate the model's ability to establish a specific...
Main Authors: | Venita Gresham Watson, Alison Motsinger-Reif, Nicholas E Hardison, Eric J Peters, Tammy M Havener, Lorraine Everitt, James Todd Auman, Daniel L Comins, Howard L McLeod |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-05-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3088663?pdf=render |
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