Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis

Platelet over-activation is one of the important mechanisms of atherosclerosis (AS) in diabetes mellitus. Dietary nutrient intervention plays an important role in the primary prevention and treatment of diabetes mellitus combined with AS. Studies have shown that the antiplatelet factor in tomato ext...

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Main Authors: CAI Huan, JIANG Yan, LIU Jingqin, TAN Sijie, QI Feng
Format: Article
Language:zho
Published: The Editorial Office of Chinese Journal of Food Hygiene 2022-05-01
Series:Zhongguo shipin weisheng zazhi
Subjects:
Online Access:http://www.zgspws.com/zgspwszz/article/abstract/202203024?st=article_issue
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author CAI Huan
JIANG Yan
LIU Jingqin
TAN Sijie
QI Feng
author_facet CAI Huan
JIANG Yan
LIU Jingqin
TAN Sijie
QI Feng
author_sort CAI Huan
collection DOAJ
description Platelet over-activation is one of the important mechanisms of atherosclerosis (AS) in diabetes mellitus. Dietary nutrient intervention plays an important role in the primary prevention and treatment of diabetes mellitus combined with AS. Studies have shown that the antiplatelet factor in tomato extract can inhibit platelet aggregation and activation in different environments. Its bioactive ingredient are nucleosides and derivatives and phenolic compounds, which retard the pathological progress of diabetes mellitus complicated with AS. This review aims to explore the mechanism of the antiplatelet effect of tomato extract, and to provide a theoretical basis for the prevention and treatment of diabetes mellitus complicated with AS.
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spelling doaj.art-71b7da1e9a07458a86bcefdeaa7b48b82022-12-27T09:24:49ZzhoThe Editorial Office of Chinese Journal of Food HygieneZhongguo shipin weisheng zazhi1004-84562022-05-0134355255610.13590/j.cjfh.2022.03.0241004-8456(2022)03-0552-05Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosisCAI Huan0JIANG Yan1LIU Jingqin2TAN Sijie3QI Feng4Tianjin University of Sport, College of Exercise and Health Sciences,Tianjin 301617, ChinaTianjin University of Sport, College of Exercise and Health Sciences,Tianjin 301617, ChinaDepartment of Endocrinology, NO.1 Hospital of Baoding, Hebei Baoding 071000, ChinaResearch Center for Exercise & Health Science, Tianjin University of Sport, Tianjin 301617, ChinaDepartment of Endocrinology, NO.1 Hospital of Baoding, Hebei Baoding 071000, ChinaPlatelet over-activation is one of the important mechanisms of atherosclerosis (AS) in diabetes mellitus. Dietary nutrient intervention plays an important role in the primary prevention and treatment of diabetes mellitus combined with AS. Studies have shown that the antiplatelet factor in tomato extract can inhibit platelet aggregation and activation in different environments. Its bioactive ingredient are nucleosides and derivatives and phenolic compounds, which retard the pathological progress of diabetes mellitus complicated with AS. This review aims to explore the mechanism of the antiplatelet effect of tomato extract, and to provide a theoretical basis for the prevention and treatment of diabetes mellitus complicated with AS.http://www.zgspws.com/zgspwszz/article/abstract/202203024?st=article_issuetomato extractdiabetes mellitusatherosclerosisplatelet activation
spellingShingle CAI Huan
JIANG Yan
LIU Jingqin
TAN Sijie
QI Feng
Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis
Zhongguo shipin weisheng zazhi
tomato extract
diabetes mellitus
atherosclerosis
platelet activation
title Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis
title_full Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis
title_fullStr Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis
title_full_unstemmed Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis
title_short Mechanism of tomato extract against platelet over-activation in diabetic atherosclerosis
title_sort mechanism of tomato extract against platelet over activation in diabetic atherosclerosis
topic tomato extract
diabetes mellitus
atherosclerosis
platelet activation
url http://www.zgspws.com/zgspwszz/article/abstract/202203024?st=article_issue
work_keys_str_mv AT caihuan mechanismoftomatoextractagainstplateletoveractivationindiabeticatherosclerosis
AT jiangyan mechanismoftomatoextractagainstplateletoveractivationindiabeticatherosclerosis
AT liujingqin mechanismoftomatoextractagainstplateletoveractivationindiabeticatherosclerosis
AT tansijie mechanismoftomatoextractagainstplateletoveractivationindiabeticatherosclerosis
AT qifeng mechanismoftomatoextractagainstplateletoveractivationindiabeticatherosclerosis