Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD
Background and objective Dynamic lung hyperinflation (DLH) can play a central role in exertional dyspnoea in patients with COPD. Chest radiography is the basic tool for assessing static lung hyperinflation in COPD. However, the predictive capacity of DLH using chest radiography remains unknown. This...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2023-06-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/9/3/00079-2023.full |
| _version_ | 1797689346351955968 |
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| author | Masashi Shiraishi Yuji Higashimoto Ryuji Sugiya Hiroki Mizusawa Yu Takeda Masaya Noguchi Osamu Nishiyama Ryo Yamazaki Shintarou Kudo Tamotsu Kimura Yuji Tohda Hisako Matsumoto |
| author_facet | Masashi Shiraishi Yuji Higashimoto Ryuji Sugiya Hiroki Mizusawa Yu Takeda Masaya Noguchi Osamu Nishiyama Ryo Yamazaki Shintarou Kudo Tamotsu Kimura Yuji Tohda Hisako Matsumoto |
| author_sort | Masashi Shiraishi |
| collection | DOAJ |
| description | Background and objective
Dynamic lung hyperinflation (DLH) can play a central role in exertional dyspnoea in patients with COPD. Chest radiography is the basic tool for assessing static lung hyperinflation in COPD. However, the predictive capacity of DLH using chest radiography remains unknown. This study was conducted to determine whether DLH can be predicted by measuring the height of the right diaphragm (dome height) on chest radiography.
Methods
This single-centre, retrospective cohort study included patients with stable COPD with pulmonary function test, cardiopulmonary exercise test, constant load test and pulmonary images. They were divided into two groups according to the median of changes of inspiratory capacity (ΔIC=IC lowest − IC at rest). The right diaphragm dome height and lung height were measured on plain chest radiography.
Results
Of the 48 patients included, 24 were classified as having higher DLH (ΔIC ≤−0.59 L from rest; −0.59 L, median of all) and 24 as having lower DLH. Dome height correlated with ΔIC (r=0.66, p<0.001). Multivariate analysis revealed that dome height was associated with higher DLH independent of % low attenuation area on chest computed tomography and forced expiratory volume in 1 s (FEV1) % predicted. Furthermore, the area under the receiver operating characteristic curve of dome height to predict higher DLH was 0.86, with sensitivity and specificity of 83% and 75%, respectively, at a cut-off of 20.5 mm. Lung height was unrelated to ΔIC.
Conclusion
Diaphragm dome height on chest radiography may adequately predict higher DLH in patients with COPD. |
| first_indexed | 2024-03-12T01:44:25Z |
| format | Article |
| id | doaj.art-71b805c646404e27852887dd91570145 |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-03-12T01:44:25Z |
| publishDate | 2023-06-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-71b805c646404e27852887dd915701452023-09-09T13:53:54ZengEuropean Respiratory SocietyERJ Open Research2312-05412023-06-019310.1183/23120541.00079-202300079-2023Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPDMasashi Shiraishi0Yuji Higashimoto1Ryuji Sugiya2Hiroki Mizusawa3Yu Takeda4Masaya Noguchi5Osamu Nishiyama6Ryo Yamazaki7Shintarou Kudo8Tamotsu Kimura9Yuji Tohda10Hisako Matsumoto11 Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Respiratory Medicine and Allergology, Kindai University School of Medicine, Osaka, Japan Department of Respiratory Medicine and Allergology, Kindai University School of Medicine, Osaka, Japan Inclusive Medical Science Research Institute, Morinomiya University of Medical Sciences, Osaka, Japan Department of Rehabilitation Medicine, Kindai University School of Medicine, Osaka, Japan Department of Respiratory Medicine and Allergology, Kindai University School of Medicine, Osaka, Japan Department of Respiratory Medicine and Allergology, Kindai University School of Medicine, Osaka, Japan Background and objective Dynamic lung hyperinflation (DLH) can play a central role in exertional dyspnoea in patients with COPD. Chest radiography is the basic tool for assessing static lung hyperinflation in COPD. However, the predictive capacity of DLH using chest radiography remains unknown. This study was conducted to determine whether DLH can be predicted by measuring the height of the right diaphragm (dome height) on chest radiography. Methods This single-centre, retrospective cohort study included patients with stable COPD with pulmonary function test, cardiopulmonary exercise test, constant load test and pulmonary images. They were divided into two groups according to the median of changes of inspiratory capacity (ΔIC=IC lowest − IC at rest). The right diaphragm dome height and lung height were measured on plain chest radiography. Results Of the 48 patients included, 24 were classified as having higher DLH (ΔIC ≤−0.59 L from rest; −0.59 L, median of all) and 24 as having lower DLH. Dome height correlated with ΔIC (r=0.66, p<0.001). Multivariate analysis revealed that dome height was associated with higher DLH independent of % low attenuation area on chest computed tomography and forced expiratory volume in 1 s (FEV1) % predicted. Furthermore, the area under the receiver operating characteristic curve of dome height to predict higher DLH was 0.86, with sensitivity and specificity of 83% and 75%, respectively, at a cut-off of 20.5 mm. Lung height was unrelated to ΔIC. Conclusion Diaphragm dome height on chest radiography may adequately predict higher DLH in patients with COPD.http://openres.ersjournals.com/content/9/3/00079-2023.full |
| spellingShingle | Masashi Shiraishi Yuji Higashimoto Ryuji Sugiya Hiroki Mizusawa Yu Takeda Masaya Noguchi Osamu Nishiyama Ryo Yamazaki Shintarou Kudo Tamotsu Kimura Yuji Tohda Hisako Matsumoto Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD ERJ Open Research |
| title | Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD |
| title_full | Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD |
| title_fullStr | Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD |
| title_full_unstemmed | Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD |
| title_short | Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD |
| title_sort | diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in copd |
| url | http://openres.ersjournals.com/content/9/3/00079-2023.full |
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