Effects of different durations of pretreatment with losartan on myocardial infarct size, endothelial function, and vascular endothelial growth factor

A previous study by our group showed that 10 weeks of pretreatment with losartan reduced myocardial infarct size and arrhythmias in a rat model of ischaemia-reperfusion. However, the effect of a differing time course of pretreatment has not been investigated. 104 Sprague-Dawley rats were randomised...

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Bibliographic Details
Main Authors: Bo-qing Zhu, Yi-ping Sun, Richard E Sievers, Amanda EM Browne, Randall J Lee, Kanu Chatterjee, William W Parmley
Format: Article
Language:English
Published: SAGE Publications 2001-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2001.014

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