Effects of different durations of pretreatment with losartan on myocardial infarct size, endothelial function, and vascular endothelial growth factor
A previous study by our group showed that 10 weeks of pretreatment with losartan reduced myocardial infarct size and arrhythmias in a rat model of ischaemia-reperfusion. However, the effect of a differing time course of pretreatment has not been investigated. 104 Sprague-Dawley rats were randomised...
Main Authors: | Bo-qing Zhu, Yi-ping Sun, Richard E Sievers, Amanda EM Browne, Randall J Lee, Kanu Chatterjee, William W Parmley |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2001-06-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2001.014 |
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